Literature DB >> 34046784

Generation of Reactive Oxygen Species by Human Whole Blood Cells Exposed to Iron Oxide Magnetic Nanoparticles Coated with Different Shells.

Ya G Toropova1, D S Motorina2, I А Zelinskaya2, D V Korolev2, G А Schulmeister2, Yu А Skorik2.   

Abstract

We compared dose-dependent influence of magnetic nanoparticles (MNP) coated with different shells on ROS generation during incubation with whole human blood. ROS generation was evaluated using luminol dependent chemiluminescence. MNP with polylactide shell in concentrations of 0.2-2.0 mg/ml had no effect on spontaneous chemiluminescence, while MNP with polysaccharide shell induced a dose dependent enhanced spontaneous chemiluminescence that increased during incubation (1-3 h). MNP with albumin shell in concentrations of 0.2 mg/ml gradually enhanced spontaneous chemiluminescence during incubation, but increasing the concentration neutralized this effect.

Entities:  

Keywords:  ROS; chemiluminescence; dosedependence; iron oxide nanoparticles; whole blood

Mesh：

Substances：

Year:  2021        PMID： 34046784     DOI： 10.1007/s10517-021-05176-6

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  10 in total

1.  The size-dependent genotoxic potentials of titanium dioxide nanoparticles to endothelial cells.

Authors:  Fen Liao; Lingying Chen; Yuanfeng Liu; Dongting Zhao; Wenyi Peng; Wuxiang Wang; Shaolong Feng
Journal:  Environ Toxicol       Date:  2019-07-11       Impact factor: 4.119

2.  Iron oxide nanoparticles induced cytotoxicity, oxidative stress and DNA damage in lymphocytes.

Authors:  Usha Singh Gaharwar; Ramovatar Meena; Paulraj Rajamani
Journal:  J Appl Toxicol       Date:  2017-06-06       Impact factor: 3.446

Review 3.  Nanoparticles for biomedical imaging.

Authors:  Satish K Nune; Padmaja Gunda; Praveen K Thallapally; Ying-Ying Lin; M Laird Forrest; Cory J Berkland
Journal:  Expert Opin Drug Deliv       Date:  2009-11       Impact factor: 6.648

Review 4.  Nanoparticles for hyperthermic therapy: synthesis strategies and applications in glioblastoma.

Authors:  Jyoti Verma; Sumit Lal; Cornelis J F Van Noorden
Journal:  Int J Nanomedicine       Date:  2014-06-10

Review 5.  Nanotoxicity: An Interplay of Oxidative Stress, Inflammation and Cell Death.

Authors:  Puja Khanna; Cynthia Ong; Boon Huat Bay; Gyeong Hun Baeg
Journal:  Nanomaterials (Basel)       Date:  2015-06-30       Impact factor: 5.076

6.  In vitro toxicity of FemOn, FemOn-SiO2 composite, and SiO2-FemOn core-shell magnetic nanoparticles.

Authors:  Yana G Toropova; Alexey S Golovkin; Anna B Malashicheva; Dmitry V Korolev; Andrey N Gorshkov; Kamil G Gareev; Michael V Afonin; Michael M Galagudza
Journal:  Int J Nanomedicine       Date:  2017-01-13

Review 7.  Magnetic Drug Delivery: Where the Field Is Going.

Authors:  Paige M Price; Waleed E Mahmoud; Ahmed A Al-Ghamdi; Lyudmila M Bronstein
Journal:  Front Chem       Date:  2018-12-11       Impact factor: 5.221

8.  A green approach for the synthesis of α-Fe2O3 nanoparticles from Gardenia resinifera plant and it's In vitro hyperthermia application.

Authors:  V C Karade; S B Parit; V V Dawkar; R S Devan; R J Choudhary; V V Kedge; N V Pawar; J H Kim; A D Chougale
Journal:  Heliyon       Date:  2019-07-10

9.  Uptake, distribution, clearance, and toxicity of iron oxide nanoparticles with different sizes and coatings.

Authors:  Qiyi Feng; Yanping Liu; Jian Huang; Ke Chen; Jinxing Huang; Kai Xiao
Journal:  Sci Rep       Date:  2018-02-01       Impact factor: 4.379

10.  Biomarkers of oxidative stress for in vivo assessment of toxicological effects of iron oxide nanoparticles.

Authors:  Utkarsh A Reddy; P V Prabhakar; M Mahboob
Journal:  Saudi J Biol Sci       Date:  2015-09-30       Impact factor: 4.219
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.