| Literature DB >> 3404583 |
J Richter1, I Puchtler, B Fleckenstein.
Abstract
The putative thymidylate synthase (TS) gene of herpesvirus ateles, a T-lymphotropic tumor virus of New World primates, has a single large open reading frame encoding a polypeptide of 32.9 kilodaltons. The gene is transcribed into an unspliced 2.4-kilobase mRNA that is abundantly expressed late in virus replication. The AT-rich 5' untranslated leader sequence of TS mRNA in herpesvirus ateles-infected cells is remarkable in length (1,184 nucleotides), containing 29 minicistrons; this may indicate a role in translation regulation.Entities:
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Year: 1988 PMID: 3404583 PMCID: PMC253484
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103