Literature DB >> 340458

The RNA primer synthesized by primase to initiate phage G4 DNA replication.

J P Bouché, L Rowen, A Kornberg.   

Abstract

With phage G4 DNA as template, primase (the dnaG protein) synthesizes a 26- to 29-residue RNA transcript at the origin of replication. The sequence starts with ATP and contains a hairpin region of one A-U and seven G-C base pairs. Covalent linkage between the RNA and the newly synthesized complementary DNA chain indicates that the RNA transcript serves as a primer.

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Year:  1978        PMID： 340458

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  42 in total

1.  Dimers of pi protein bind the A+T-rich region of the R6K gamma origin near the leading-strand synthesis start sites: regulatory implications.

Authors:  R Krüger; M Filutowicz
Journal:  J Bacteriol       Date:  2000-05       Impact factor: 3.490

2.  A general priming system employing only dnaB protein and primase for DNA replication.

Authors:  K Arai; A Kornberg
Journal:  Proc Natl Acad Sci U S A       Date:  1979-09       Impact factor: 11.205

3.  Structural features of the priming signal recognized by primase: mutational analysis of the phage G4 origin of complementary DNA strand synthesis.

Authors:  H Hiasa; H Sakai; T Komano; G N Godson
Journal:  Nucleic Acids Res       Date:  1990-08-25       Impact factor: 16.971

4.  Initiation of enzymatic replication at the origin of the Escherichia coli chromosome: primase as the sole priming enzyme.

Authors:  A van der Ende; T A Baker; T Ogawa; A Kornberg
Journal:  Proc Natl Acad Sci U S A       Date:  1985-06       Impact factor: 11.205

5.  DnaG-dependent priming signals can substitute for the two essential DNA initiation signals in oriV of the broad host-range plasmid RSF1010.

Authors:  Y Honda; T Nakamura; K Tanaka; A Higashi; H Sakai; T Komano; M Bagdasarian
Journal:  Nucleic Acids Res       Date:  1992-04-11       Impact factor: 16.971

6.  Replication of single-stranded plasmid pT181 DNA in vitro.

Authors:  P Birch; S A Khan
Journal:  Proc Natl Acad Sci U S A       Date:  1992-01-01       Impact factor: 11.205

7.  Ribonucleotidyl transferase in preparations of partially purified DNA polymerase alpha of the sea urchin.

Authors:  P W Morris; F M Racine
Journal:  Nucleic Acids Res       Date:  1978-10       Impact factor: 16.971

8.  Transgenically expressed T-Rep of tomato yellow leaf curl Sardinia virus acts as a trans-dominant-negative mutant, inhibiting viral transcription and replication.

Authors:  A Brunetti; R Tavazza; E Noris; A Lucioli; G P Accotto; M Tavazza
Journal:  J Virol       Date:  2001-11       Impact factor: 5.103

9.  Replication initiation at a distance: determination of the cis- and trans-acting elements of replication origin alpha of plasmid R6K.

Authors:  Mukesh Saxena; Mayuresh Abhyankar; Deepak Bastia
Journal:  J Biol Chem       Date:  2009-12-15       Impact factor: 5.157

10.  Comparative analysis of functional and structural features in the primase-dependent priming signals, G sites, from phages and plasmids.

Authors:  K Tanaka; T Rogi; H Hiasa; D M Miao; Y Honda; N Nomura; H Sakai; T Komano
Journal:  J Bacteriol       Date:  1994-06       Impact factor: 3.490
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