Literature DB >> 34044802

Relationships between age at first substance use and persistence of cannabis use and cannabis use disorder.

Seán R Millar1,2, Deirdre Mongan3, Bobby P Smyth4, Ivan J Perry5, Brian Galvin3.   

Abstract

BACKGROUND: From a secondary prevention perspective, it is useful to know who is at greatest risk of progressing from substance initiation to riskier patterns of future use. Therefore, the aim of this study was to determine relationships between age at first use of alcohol, tobacco and cannabis and patterns of cannabis use, frequency of use and whether age of substance use onset is related to having a cannabis use disorder (CUD).
METHODS: We analysed data from Ireland's 2010/11 and 2014/15 National Drug Prevalence Surveys, which recruited 5134 and 7005 individuals respectively, aged 15 years and over, living in private households. We included only those people who reported lifetime cannabis use. Multinomial, linear and binary logistic regression analyses were used to determine relationships between age of substance use onset and patterns of cannabis use, frequency of use and having a CUD.
RESULTS: When compared to former users, the odds of being a current cannabis user were found to be reduced by 11% (OR = 0.89; 95% CI: 0.83, 0.95) and 4% (OR = 0.96; 95% CI: 0.92, 1.00) for each year of delayed alcohol and cannabis use onset, respectively. Among current users, significant inverse linear relationships were noted, with increasing age of first use of tobacco (β = - 0.547; P < .001) and cannabis (β = - 0.634; P < .001) being associated with a decreased frequency of cannabis use within the last 30 days. The odds of having a CUD were found to be reduced by 14% (OR = 0.86; 95% CI: 0.78, 0.94) and 11% (OR = 0.89; 95% CI: 0.82, 0.98) for each year of delayed tobacco and cannabis use onset respectively in analyses which examined survey participants aged 15-34 years.
CONCLUSIONS: Among people who report past cannabis use, it is those with a more precocious pattern of early use of substances, including alcohol, and especially tobacco and cannabis, who are more likely to report ongoing, heavy and problematic cannabis use. Secondary prevention initiatives should prioritise people with a pattern of very early onset substance use.

Entities:  

Keywords:  Abuse; Age; Alcohol; Cannabis; Dependence; Onset; Tobacco; Use

Year:  2021        PMID: 34044802     DOI: 10.1186/s12889-021-11023-0

Source DB:  PubMed          Journal:  BMC Public Health        ISSN: 1471-2458            Impact factor:   3.295


  26 in total

1.  The relevance of age at first alcohol and nicotine use for initiation of cannabis use and progression to cannabis use disorders.

Authors:  Silke Behrendt; Katja Beesdo-Baum; Michael Höfler; Axel Perkonigg; Gerhard Bühringer; Roselind Lieb; Hans-Ulrich Wittchen
Journal:  Drug Alcohol Depend       Date:  2011-11-08       Impact factor: 4.492

2.  Can the gateway hypothesis, the common liability model and/or, the route of administration model predict initiation of cannabis use during adolescence? A survival analysis--the TRAILS study.

Authors:  Andrea Prince van Leeuwen; Frank C Verhulst; Sijmen A Reijneveld; Wilma A M Vollebergh; Johan Ormel; Anja C Huizink
Journal:  J Adolesc Health       Date:  2010-08-30       Impact factor: 5.012

Review 3.  Neurobiology of the adolescent brain and behavior: implications for substance use disorders.

Authors:  B J Casey; Rebecca M Jones
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2010-10-08       Impact factor: 8.829

Review 4.  Cannabis Use among People Entering Drug Treatment in Europe: A Growing Phenomenon?

Authors:  Linda Montanari; Bruno Guarita; Jane Mounteney; Nina Zipfel; Roland Simon
Journal:  Eur Addict Res       Date:  2017-05-17       Impact factor: 3.015

5.  Structure of problem behavior in adolescence and young adulthood.

Authors:  J E Donovan; R Jessor
Journal:  J Consult Clin Psychol       Date:  1985-12

Review 6.  Effects of adolescent alcohol consumption on the brain and behaviour.

Authors:  Linda P Spear
Journal:  Nat Rev Neurosci       Date:  2018-02-15       Impact factor: 34.870

7.  Association between early onset of cigarette, alcohol and cannabis use and later drug use patterns: an analysis of a survey in European metropolises.

Authors:  S E Baumeister; P Tossmann
Journal:  Eur Addict Res       Date:  2005       Impact factor: 3.015

Review 8.  Cannabis and adolescent brain development.

Authors:  Dan I Lubman; Ali Cheetham; Murat Yücel
Journal:  Pharmacol Ther       Date:  2014-11-20       Impact factor: 12.310

9.  Grey Matter Volume Differences Associated with Extremely Low Levels of Cannabis Use in Adolescence.

Authors:  Catherine Orr; Philip Spechler; Zhipeng Cao; Matthew Albaugh; Bader Chaarani; Scott Mackey; Deepak D'Souza; Nicholas Allgaier; Tobias Banaschewski; Arun L W Bokde; Uli Bromberg; Christian Büchel; Erin Burke Quinlan; Patricia Conrod; Sylvane Desrivières; Herta Flor; Vincent Frouin; Penny Gowland; Andreas Heinz; Bernd Ittermann; Jean-Luc Martinot; Marie-Laure Paillère Martinot; Frauke Nees; Dimitri Papadopoulos Orfanos; Tomáš Paus; Luise Poustka; Sabina Millenet; Juliane H Fröhner; Rajiv Radhakrishnan; Michael N Smolka; Henrik Walter; Robert Whelan; Gunter Schumann; Alexandra Potter; Hugh Garavan
Journal:  J Neurosci       Date:  2019-01-14       Impact factor: 6.167

10.  Are adolescents more vulnerable to the harmful effects of cannabis than adults? A placebo-controlled study in human males.

Authors:  C Mokrysz; T P Freeman; S Korkki; K Griffiths; H V Curran
Journal:  Transl Psychiatry       Date:  2016-11-29       Impact factor: 6.222

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.