Syeda Sahra1, Abdullah Jahangir2, Neville Mobarakai2, Allison Glaser2, Ahmad Jahangir3, Muhammad Ans Sharif3. 1. Staten Island University Hospital, 475-Seaview Avenue, Staten Island, NY, 10305, USA. ssahra@northwell.edu. 2. Staten Island University Hospital, 475-Seaview Avenue, Staten Island, NY, 10305, USA. 3. King Edward Medical University, Lahore, 54000, Pakistan.
Abstract
INTRODUCTION: Cronobacter sakazakii is an opportunistic Gram-negative, rod-shaped bacterium which may be a causative agent of meningitis in premature infants and enterocolitis and bacteremia in neonates and adults. While there have been multiple cases of C. sakazakii infections, there have been no acute cholangitis cases reported in humans. CASE PRESENTATION: An 81-year-old male with a past medical history of basal cell carcinoma, alcoholic liver cirrhosis, transjugular intrahepatic portosystemic shunt procedure, complicated by staphylococcus bacteremia, pituitary tumor, glaucoma, and hypothyroidism presented to the emergency room with the complaint of diffuse and generalized 10/10 abdominal pain of 1 day's duration. There was a concern for pancreatitis, acute cholangitis, and possible cholecystitis, and the patient underwent a percutaneous cholecystostomy tube placement. Blood cultures from admission and biliary fluid cultures both grew C. sakazakii. The patient was treated with a carbapenem and clinically improved. CONCLUSIONS: The case study described a patient with multiple medical comorbidities that presented with C. sakazakii bacteremia and cholangitis. While this bacterium has been implicated in other infections, we believe this is the first time the bacteria is being documented to have caused acute cholangitis.
INTRODUCTION:Cronobacter sakazakii is an opportunistic Gram-negative, rod-shaped bacterium which may be a causative agent of meningitis in premature infants and enterocolitis and bacteremia in neonates and adults. While there have been multiple cases of C. sakazakiiinfections, there have been no acute cholangitis cases reported in humans. CASE PRESENTATION: An 81-year-old male with a past medical history of basal cell carcinoma, alcoholic liver cirrhosis, transjugular intrahepatic portosystemic shunt procedure, complicated by staphylococcus bacteremia, pituitary tumor, glaucoma, and hypothyroidism presented to the emergency room with the complaint of diffuse and generalized 10/10 abdominal pain of 1 day's duration. There was a concern for pancreatitis, acute cholangitis, and possible cholecystitis, and the patient underwent a percutaneous cholecystostomy tube placement. Blood cultures from admission and biliary fluid cultures both grew C. sakazakii. The patient was treated with a carbapenem and clinically improved. CONCLUSIONS: The case study described a patient with multiple medical comorbidities that presented with C. sakazakiibacteremia and cholangitis. While this bacterium has been implicated in other infections, we believe this is the first time the bacteria is being documented to have caused acute cholangitis.
Authors: M Chantal Kandhai; Martine W Reij; Leon G M Gorris; Olivier Guillaume-Gentil; Mike van Schothorst Journal: Lancet Date: 2004-01-03 Impact factor: 79.321
Authors: M C Kandhai; M W Reij; K van Puyvelde; O Guillaume-Gentil; R R Beumer; M van Schothorst Journal: J Food Prot Date: 2004-06 Impact factor: 2.077
Authors: A Alsonosi; S Hariri; M Kajsík; M Oriešková; V Hanulík; M Röderová; J Petrželová; H Kollárová; H Drahovská; S Forsythe; O Holý Journal: Eur J Clin Microbiol Infect Dis Date: 2015-07-15 Impact factor: 3.267
Authors: Cláudia Elizabeth Volpe Chaves; Marcelo Luiz Lima Brandão; Mara Luci Gonçalves Galiz Lacerda; Caroline Aparecida Barbosa Coelho Rocha; Sandra Maria do Valle Leone de Oliveira; Tânia Cristina Parpinelli; Luiza Vasconcellos; Stephen James Forsythe; Anamaria Mello Miranda Paniago Journal: Emerg Infect Dis Date: 2018-10 Impact factor: 6.883