| Literature DB >> 34040312 |
Sampath Santhosh1, Godwin Jeeva1, Ranjan Kumar Mohapatra2.
Abstract
An elderly male on androgen deprivation therapy for prostatic adenocarcinoma presented with obstructive jaundice. Since biopsy from the head of the pancreas showed neuroendocrine carcinoma (NEC), he was diagnosed with second primary pancreatic NEC. Ga-68 DOTANOC positron emission tomography/computed tomography (PET/CT) done subsequently showed enlarged mildly DOTANOC-avid retroperitoneal nodes infiltrating the pancreas. These nodes were found to be progression of prostate-specific membrane antigen (PSMA) nonavid retroperitoneal nodes visualized in his Ga-68 PSMA PET/CT performed at another institution before 4 months, when there was no lesion in the pancreas. This observation revised the diagnosis from second primary pancreatic NEC to progression of neuroendocrine differentiation in preexisting prostatic adenocarcinoma. Copyright:Entities:
Keywords: Ga-68 DOTANOC; Ga-68 prostate-specific membrane antigen; jaundice; neuroendocrine differentiation; positron emission tomography/computed tomography; prostatic adenocarcinoma
Year: 2021 PMID： 34040312 PMCID： PMC8130684 DOI： 10.4103/ijnm.IJNM_127_20
Source DB: PubMed Journal: Indian J Nucl Med ISSN： 0974-0244