Literature DB >> 34038982

Evaluating the impact of the Patient Preference Assessment Tool on clinicians' recommendations for phase I oncology clinical trials.

Rachel S Hianik1, Taofeek Owonikoko1,2, Jeffrey Switchenko3, Margie D Dixon1,2, Walid L Shaib1,2, Rebecca D Pentz1,2.   

Abstract

OBJECTIVE: Many groups recommend assessment of patient preferences particularly for patients with advanced, incurable cancer. We, therefore, developed the Patient Preference Assessment Tool (PPAT) to ascertain patient preferences in order to inform clinician recommendations and improve shared decision-making. The aim of this study is to assess the PPAT's impact on clinicians' strength of recommendations for phase I oncology clinical trials.
METHODS: Clinicians recorded the strength of their recommendation on a Likert scale before viewing the patient's PPAT. After viewing the PPAT, the clinician discussed the clinical trial with the patient and then recorded the strength of recommendation again. If there was a change, the clinician noted the reason for the change: clinical findings or patient preference. Clinicians were interviewed about the acceptability of the tool. Our threshold for determining if a change in recommendation due to the PPAT was significant was 20%, given the multiple factors influencing a clinician's recommendation. We also noted the type of phase I conversation observed based on classifications defined in prior work-priming, treatment-options, trial logistics, consent.
RESULTS: N = 29. The strength of the clinicians' recommendations changed due to patient preferences in 7 of 29 (24%) of the conversations. The seven changes due to preferences were all in the 23 treatment-options conversations, for an impact rate of 30% in this type of conversation. 82% of clinicians found the PPAT useful.
CONCLUSION: The PPAT was impactful in an academic setting, exceeding our 20% impact threshold. This tool helps achieve the important goal of incorporating patient preferences into shared decision-making about clinical trials.
© 2021 John Wiley & Sons Ltd.

Entities:  

Keywords:  cancer; oncology; patient preferences; phase I clinical trials; physician recommendation; psycho-oncology

Mesh:

Year:  2021        PMID: 34038982      PMCID: PMC8497404          DOI: 10.1002/pon.5739

Source DB:  PubMed          Journal:  Psychooncology        ISSN: 1057-9249            Impact factor:   3.894


  9 in total

1.  Seeking informed consent to Phase I cancer clinical trials: identifying oncologists' communication strategies.

Authors:  Richard Brown; Carma L Bylund; Laura A Siminoff; Susan F Slovin
Journal:  Psychooncology       Date:  2010-04-07       Impact factor: 3.894

2.  Enhancing decision making about participation in cancer clinical trials: development of a question prompt list.

Authors:  Richard F Brown; Elyse Shuk; Natasha Leighl; Phyllis Butow; Jamie Ostroff; Shawna Edgerson; Martin Tattersall
Journal:  Support Care Cancer       Date:  2010-07-01       Impact factor: 3.603

Review 3.  A review of question prompt lists used in the oncology setting with comparison to the Patient Concerns Inventory.

Authors:  N Miller; S N Rogers
Journal:  Eur J Cancer Care (Engl)       Date:  2016-03-14       Impact factor: 2.520

4.  American society of clinical oncology statement: toward individualized care for patients with advanced cancer.

Authors:  Jeffrey M Peppercorn; Thomas J Smith; Paul R Helft; David J Debono; Scott R Berry; Dana S Wollins; Daniel M Hayes; Jamie H Von Roenn; Lowell E Schnipper
Journal:  J Clin Oncol       Date:  2011-01-24       Impact factor: 44.544

5.  Development and testing of a tool to assess patient preferences for phase I clinical trial participation.

Authors:  Rebecca D Pentz; Kristopher A Hendershot; Louisa Wall; Taylor E White; Susan K Peterson; Cheryl B Thomas; Jennifer McCormick; Michael J Green; Colleen Lewis; Zachary Luke Farmer; Fay J Hlubocky; Tehseen Dossul; Margie D Dixon; Yuan Liu; Jeffrey M Switchenko; Carolina Salvador; Taofeek K Owonikoko; R Donald Harvey; Fadlo R Khuri
Journal:  Psychooncology       Date:  2014-12-19       Impact factor: 3.894

6.  Informed consent for phase I studies: evaluation of quantity and quality of information provided to patients.

Authors:  M Tomamichel; C Sessa; S Herzig; J de Jong; O Pagani; Y Willems; F Cavalli
Journal:  Ann Oncol       Date:  1995-04       Impact factor: 32.976

7.  Perceptions of patients and physicians regarding phase I cancer clinical trials: implications for physician-patient communication.

Authors:  Neal J Meropol; Kevin P Weinfurt; Caroline B Burnett; Andrew Balshem; Al B Benson; Liana Castel; Sandra Corbett; Michael Diefenbach; Darrell Gaskin; Yun Li; Sharon Manne; John Marshall; Julia H Rowland; Elyse Slater; Daniel P Sulmasy; David Van Echo; Shakira Washington; Kevin A Schulman
Journal:  J Clin Oncol       Date:  2003-07-01       Impact factor: 44.544

8.  Description of the types and content of phase 1 clinical trial consent conversations in practice.

Authors:  Louisa Wall; Zachary Luke Farmer; Margaret White Webb; Margie D Dixon; Ajay Nooka; Rebecca D Pentz
Journal:  Clin Trials       Date:  2015-08-28       Impact factor: 2.486

9.  Clinician and cancer patient views on patient participation in treatment decision-making: a quantitative and qualitative exploration.

Authors:  A H Pieterse; M C M Baas-Thijssen; C A M Marijnen; A M Stiggelbout
Journal:  Br J Cancer       Date:  2008-09-16       Impact factor: 7.640

  9 in total
  1 in total

Review 1.  Advances in Treatment of Recurrent Small Cell Lung Cancer (SCLC): Insights for Optimizing Patient Outcomes from an Expert Roundtable Discussion.

Authors:  Millie Das; Sukhmani K Padda; Jared Weiss; Taofeek K Owonikoko
Journal:  Adv Ther       Date:  2021-09-26       Impact factor: 3.845

  1 in total

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