Literature DB >> 34037955

Effect of moderate aerobic exercises on symptoms of functional dyspepsia.

Siddhesh Vijay Rane1, Bharati Asgaonkar2, Pravin Rathi3, Qais Contractor3, Sanjay Chandnani3, Parmeshwar Junare3, Prasanta Debnath3, Vidya Bhat2.   

Abstract

BACKGROUND: Functional dyspepsia (FD) is a commonly encountered entity worldwide and is difficult to treat. Most of the treatment modalities have low-quality evidence for use, except for proton pump inhibitors. Aerobic exercise has been shown to improve the symptoms, but its direct effect on symptoms has never been studied. The objective was to study the effects of moderate aerobic exercise on symptoms of FD and to compare the effect of conventional treatment alone vs. exercise plus conventional treatment.
METHODS: Out of 112 patients, 72 were randomly divided into controls (conventional treatment; n=36) and experimental (aerobic exercise for 30 min per session, 5 times a week for 6 weeks with conventional treatment; n=36) groups. Both the groups were assessed on day 1 and at the end of 6 weeks, using Glasgow Dyspepsia Severity Score (GDSS), Depression Anxiety Stress Scales-42 (DASS-42), and visual analogue scale (VAS).
RESULTS: Pre-treatment GDSS, DASS-42, and VAS in the experimental group were significantly different as compared to the post-treatment scores (p=0.00019, p=0.0002, p=0.00019, respectively). Even in the control group, pre- and post-treatment GDSS, DASS-42, and VAS scores were significantly different (p=0.00019, p=0.0002, p=0.00019, respectively). However, on the head-to-head comparison of the 2 groups, scores at the end of 6 weeks were significantly different (p< 0.05), in favor of the experimental group.
CONCLUSION: Aerobic exercise as an auxiliary therapy to conventional treatment has better outcomes in the functional well-being of dyspepsia.

Entities:  

Keywords:  Aerobic exercise; Depression Anxiety Stress Scales-42; Dyspepsia; Endorphins; Gastrointestinal microbiome; Glasgow Dyspepsia Severity Score; Psychological stress; Quality of life; Visual analogue scale

Mesh:

Substances:

Year:  2021        PMID: 34037955     DOI: 10.1007/s12664-021-01174-8

Source DB:  PubMed          Journal:  Indian J Gastroenterol        ISSN: 0254-8860


  43 in total

Review 1.  Pathophysiology and treatment of functional dyspepsia.

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Journal:  Gastroenterology       Date:  2004-10       Impact factor: 22.682

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Review 3.  Metabolic equivalents (METS) in exercise testing, exercise prescription, and evaluation of functional capacity.

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4.  Effects of cannabinoids on neuropeptide Y and β-endorphin expression in the rat hypothalamic arcuate nucleus.

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5.  Physical activity and the gastrointestinal tract.

Authors:  Magnus Simrén
Journal:  Eur J Gastroenterol Hepatol       Date:  2002-10       Impact factor: 2.566

Review 6.  Gastroduodenal Disorders.

Authors:  Vincenzo Stanghellini; Francis K L Chan; William L Hasler; Juan R Malagelada; Hidekazu Suzuki; Jan Tack; Nicholas J Talley
Journal:  Gastroenterology       Date:  2016-05       Impact factor: 22.682

Review 7.  Definition, Pathogenesis, and Management of That Cursed Dyspepsia.

Authors:  Pramoda Koduru; Malcolm Irani; Eamonn M M Quigley
Journal:  Clin Gastroenterol Hepatol       Date:  2017-09-09       Impact factor: 11.382

8.  Aerobic Exercise Increases Meteorin-Like Protein in Muscle and Adipose Tissue of Chronic High-Fat Diet-Induced Obese Mice.

Authors:  Ju Yong Bae
Journal:  Biomed Res Int       Date:  2018-04-30       Impact factor: 3.411

Review 9.  The Effect of Training Intensity on VO2max in Young Healthy Adults: A Meta-Regression and Meta-Analysis.

Authors:  Trisha D Scribbans; Stephan Vecsey; Paul B Hankinson; William S Foster; Brendon J Gurd
Journal:  Int J Exerc Sci       Date:  2016-04-01

Review 10.  Quantifying the Association Between Physical Activity and Cardiovascular Disease and Diabetes: A Systematic Review and Meta-Analysis.

Authors:  Ahad Wahid; Nishma Manek; Melanie Nichols; Paul Kelly; Charlie Foster; Premila Webster; Asha Kaur; Claire Friedemann Smith; Elizabeth Wilkins; Mike Rayner; Nia Roberts; Peter Scarborough
Journal:  J Am Heart Assoc       Date:  2016-09-14       Impact factor: 5.501

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  1 in total

1.  British Society of Gastroenterology guidelines on the management of functional dyspepsia.

Authors:  Christopher J Black; Peter A Paine; Anurag Agrawal; Imran Aziz; Maria P Eugenicos; Lesley A Houghton; Pali Hungin; Ross Overshott; Dipesh H Vasant; Sheryl Rudd; Richard C Winning; Maura Corsetti; Alexander C Ford
Journal:  Gut       Date:  2022-07-07       Impact factor: 31.793

  1 in total

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