Literature DB >> 3403776

Myocardiotoxicity of 5 fluorouracil.

B Coronel1, O Madonna, A Mercatello, A Caillette, J F Moskovtchenko.   

Abstract

We report a case of specific myocardiotoxicity due to 5 F.U. not previously described in man. A 41-year-old man was admitted to the ICU for heart and renal failure, appearing 24 h after 5 days treatment with 5 F.U. and cis-platinum. Dopamine was necessary to maintain blood pressure. Two-D echocardiography and a right heart catheterisation confirmed the alteration of myocardial contractility. After 2 weeks a complete cardiac recovery occurred.

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Year:  1988        PMID： 3403776     DOI： 10.1007/bf00262901

Source DB:  PubMed          Journal:  Intensive Care Med        ISSN： 0342-4642            Impact factor:   17.440


  4 in total

1.  [Experimental myocarditis; anatomical study of 210 rat hearts after ingestion of 5-fluorouracil].

Authors:  R Levillain
Journal:  C R Seances Soc Biol Fil       Date:  1972-11-09

Review 2.  Dilated cardiomyopathies of the adult (first of two parts).

Authors:  R A Johnson; I Palacios
Journal:  N Engl J Med       Date:  1982-10-21       Impact factor: 91.245

3.  Fluorouracil cardiotoxicity.

Authors:  A Pottage; S Holt; S Ludgate; A O Langlands
Journal:  Br Med J       Date:  1978-03-04

4.  Cardiac toxicity of 5-fluorouracil: a study on 1083 patients.

Authors:  R Labianca; G Beretta; M Clerici; P Fraschini; G Luporini
Journal:  Tumori       Date:  1982-12-31
  4 in total
  3 in total

Review 1.  Cardiotoxicity of the antiproliferative compound fluorouracil.

Authors:  K Becker; J F Erckenbrecht; D Häussinger; T Frieling
Journal:  Drugs       Date:  1999-04       Impact factor: 9.546

2.  Acute myocardiotoxicity during 5-fluorouracil therapy.

Authors:  B Misset; B Escudier; B Leclercq; D Rivara; P Rougier; G Nitenberg
Journal:  Intensive Care Med       Date:  1990       Impact factor: 17.440

3.  Effects of 5-fluorouracil on morphology, cell cycle, proliferation, apoptosis, autophagy and ROS production in endothelial cells and cardiomyocytes.

Authors:  Chiara Focaccetti; Antonino Bruno; Elena Magnani; Desirée Bartolini; Elisa Principi; Katiuscia Dallaglio; Eraldo O Bucci; Giovanna Finzi; Fausto Sessa; Douglas M Noonan; Adriana Albini
Journal:  PLoS One       Date:  2015-02-11       Impact factor: 3.240
  3 in total

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