| Literature DB >> 34037676 |
Abstract
Regulatory T cells (Tregs) are indispensable for the establishment and maintenance of immunological self-tolerance. Their genetic anomalies or variations in function are causative of various monogenic and polygenic autoimmune diseases. Treg-based reestablishment of self-tolerance is envisioned to cure autoimmune diseases in the clinic.Entities:
Year: 2021 PMID: 34037676 DOI: 10.1084/jem.20210831
Source DB: PubMed Journal: J Exp Med ISSN: 0022-1007 Impact factor: 14.307