Literature DB >> 34037640

Immune evasion of SARS-CoV-2 variants of concern is driven by low affinity to neutralizing antibodies.

Matheus V F Ferraz1, Emerson G Moreira1, Danilo F Coêlho1, Gabriel L Wallau2, Roberto D Lins2.   

Abstract

SARS-CoV-2 VOC immune evasion is mainly due to lower cross-reactivity from previously elicited class I/II neutralizing antibodies, while increased affinity to hACE2 plays a minor role. The affinity between antibodies and VOCs is impacted by remodeling of the electrostatic surface potential of the Spike RBDs. The P.3 variant is a putative VOC.

Entities:  

Year:  2021        PMID: 34037640     DOI: 10.1039/d1cc01747k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  7 in total

1.  Knowledge, perception, and fear among the global population towards newly evoked variant Omicron (B.1.1.529).

Authors:  Ali Qureshi; Syed Azhar Syed Sulaiman; Narendar Kumar; Pir Abdul Ahad Aziz Qureshi
Journal:  PLoS One       Date:  2022-07-06       Impact factor: 3.752

2.  Studies on Growth Characteristics and Cross-Neutralization of Wild-Type and Delta SARS-CoV-2 From Hisar (India).

Authors:  Nitin Khandelwal; Yogesh Chander; Ram Kumar; Himanshu Nagori; Assim Verma; Priyasi Mittal; Riyesh T; Sameer Kamboj; Sukhbir Singh Verma; Subhash Khatreja; Yash Pal; Baldev R Gulati; Bhupendra N Tripathi; Sanjay Barua; Naveen Kumar
Journal:  Front Cell Infect Microbiol       Date:  2021-11-23       Impact factor: 5.293

Review 3.  COVID-19 pandemic: the delta variant, T-cell responses, and the efficacy of developing vaccines.

Authors:  Shagnik Chattopadhyay; Sayantee Hazra; Arman Kunwar Hansda; Biswajit Biswas; Ritobrata Goswami
Journal:  Inflamm Res       Date:  2022-03-15       Impact factor: 6.986

4.  Phage-Displayed Mimotopes of SARS-CoV-2 Spike Protein Targeted to Authentic and Alternative Cellular Receptors.

Authors:  Valery A Petrenko; James W Gillespie; Laura Maria De Plano; Michael A Shokhen
Journal:  Viruses       Date:  2022-02-14       Impact factor: 5.048

Review 5.  A Detailed Overview of Immune Escape, Antibody Escape, Partial Vaccine Escape of SARS-CoV-2 and Their Emerging Variants With Escape Mutations.

Authors:  Chiranjib Chakraborty; Ashish Ranjan Sharma; Manojit Bhattacharya; Sang-Soo Lee
Journal:  Front Immunol       Date:  2022-02-09       Impact factor: 7.561

6.  Cocktail of REGN Antibodies Binds More Strongly to SARS-CoV-2 Than Its Components, but the Omicron Variant Reduces Its Neutralizing Ability.

Authors:  Hung Nguyen; Pham Dang Lan; Daniel A Nissley; Edward P O'Brien; Mai Suan Li
Journal:  J Phys Chem B       Date:  2022-04-11       Impact factor: 3.466

Review 7.  Towards novel nano-based vaccine platforms for SARS-CoV-2 and its variants of concern: Advances, challenges and limitations.

Authors:  Sally A Helmy; Rasha M El-Morsi; Soha A M Helmy; Soha M El-Masry
Journal:  J Drug Deliv Sci Technol       Date:  2022-09-08       Impact factor: 5.062

  7 in total

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