Charlene Dekonenko1, Jason D Fraser1, Katherine J Deans2,3, Mary E Fallat4, Michael Helmrath5, Rashmi Kabre6, Charles M Leys7, R Cartland Burns8, Kristine Corkumd6, Patrick A Dillon9, Cynthia Downard4, Tiffany N Wright4, Samir K Gadepalli10, Julia E Grabowski6, Edward Hernandez8, Ronald Hirschl10, Kevin N Johnson10, Jonathan E Kohler7, Matthew P Landman8, Rachel M Landisch11, Amy E Lawrence2,3, Grace Z Mak12, Peter C Minneci2,3, Beth Rymeski5, Thomas T Sato11, Bethany J Slater12, Shawn D St Peter13. 1. Department of Surgery, Children's Mercy Kansas City, Kansas City, MO, USA. 2. Center for Surgical Outcomes Research, Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, OH, USA. 3. Department of Surgery, Nationwide Children's Hospital, Columbus, OH, USA. 4. Department of Surgery, University of Louisville Norton Children's Hospital, Louisville, KY, USA. 5. Department of Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. 6. Department of Surgery, Northwestern University Lurie Children's Hospital, Chicago, IL, USA. 7. Department of Surgery, University of Wisconsin American Family Children's Hospital, Madison, WI, USA. 8. Department of Surgery, Indiana University Riley Hospital for Children, Indianapolis, IN, USA. 9. Department of Surgery, Washington University St. Louis Children's Hospital, St. Louis, MO, USA. 10. Department of Surgery, University of Michigan CS Mott Children's Hospital, Ann Arbor, MI, USA. 11. Department of Surgery, Children's Hospital of Wisconsin, Milwaukee, WI, USA. 12. Department of Surgery, University of Chicago Comer Children's Hospital, Chicago, IL, USA. 13. Department of Surgery, Children's Mercy Kansas City, Kansas City, MO, USA. sspeter@cmh.edu.
Abstract
OBJECTIVE: To provide generalizable estimates for expected outcomes of simple gastroschisis (SG) and complex gastroschisis (CG) patients from a large multi-institutional cohort for use during counseling. STUDY DESIGN: A retrospective study of 394 neonates with gastroschisis at 11 children's hospitals from January 2013 to March 2017 was performed. Analysis by Fisher's exact tests and Wilcoxon rank sum tests were performed. Outcomes of complex and simple gastroschisis are reported. RESULT: There were 315 (80%) SG and 79 (20%) CG. CG had increased time from birth to closure (6 vs 4.4 days), closure to goal feeds (69 vs 23 days), ventilator use (90% vs 73%), SSIs (31% vs 11%), NEC (14% vs 6%), PN use (71 vs 24 days), LOS (104.5 vs 33 days), and mortality (11% vs 0%). CONCLUSION: This study provides generalizable estimates for expected outcomes of patients with both SG and CG that can be utilized during counseling. CG has significantly worse in-hospital outcomes.
OBJECTIVE: To provide generalizable estimates for expected outcomes of simple gastroschisis (SG) and complex gastroschisis (CG) patients from a large multi-institutional cohort for use during counseling. STUDY DESIGN: A retrospective study of 394 neonates with gastroschisis at 11 children's hospitals from January 2013 to March 2017 was performed. Analysis by Fisher's exact tests and Wilcoxon rank sum tests were performed. Outcomes of complex and simple gastroschisis are reported. RESULT: There were 315 (80%) SG and 79 (20%) CG. CG had increased time from birth to closure (6 vs 4.4 days), closure to goal feeds (69 vs 23 days), ventilator use (90% vs 73%), SSIs (31% vs 11%), NEC (14% vs 6%), PN use (71 vs 24 days), LOS (104.5 vs 33 days), and mortality (11% vs 0%). CONCLUSION: This study provides generalizable estimates for expected outcomes of patients with both SG and CG that can be utilized during counseling. CG has significantly worse in-hospital outcomes.