Literature DB >> 34033706

Cystic fibrosis year in review 2020: Section 2 pulmonary disease, infections, and inflammation.

Nicholas J Antos1,2, Adrienne P Savant3,4.   

Abstract

The outlook for those with cystic fibrosis (CF) has never been brighter with ever increasing life expectancy and the approval of the highly effective CFTR modulators, such as elexacaftor/tezacaftor/ivacaftor. With that being said, the progressive pulmonary decline and importance of lung health, infection, and inflammation in CF remains. This review is the second part in a three-part CF Year in Review 2020. Part one focused on the literature related to CFTR modulators while part three will feature the multisystem effects related to CF. This review focuses on articles from Pediatric Pulmonology, including articles from other journals that are of particular interest to clinicians. Herein, we highlight studies published during 2020 related to CF pulmonary disease, infection, treatment, and diagnostics.
© 2021 Wiley Periodicals LLC.

Entities:  

Keywords:  clinical trials; cystic fibrosis; epidemiology; pulmonary function testing; respiratory technology

Mesh:

Substances:

Year:  2021        PMID: 34033706     DOI: 10.1002/ppul.25459

Source DB:  PubMed          Journal:  Pediatr Pulmonol        ISSN: 1099-0496


  3 in total

1.  Novel CFTR Modulators for Treating Cystic Fibrosis.

Authors:  Ram W Sabnis
Journal:  ACS Med Chem Lett       Date:  2022-04-11       Impact factor: 4.345

2.  Novel Macrocyclic 1,3,4-Oxadiazoles as CFTR Modulators for Treating Cystic Fibrosis.

Authors:  Ram W Sabnis
Journal:  ACS Med Chem Lett       Date:  2022-06-30       Impact factor: 4.632

3.  Novel Substituted Cyclopropyl Compounds as CFTR Modulators for Treating Cystic Fibrosis.

Authors:  Ram W Sabnis
Journal:  ACS Med Chem Lett       Date:  2022-09-06       Impact factor: 4.632

  3 in total

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