Cristiano Linck Pazeto1,2, Petr Macek3, Breno Amaral4, Ahmed S Zugail1,5, Kvetoslav Novak6, Michael Pesl6, Tomas Hanus6, Lenka Plincerelova6, Nathalie Cathala1, Annick Mombet1, Marine Lefèvre7, Emmanuel Chambon7, Rafael Sanchez-Salas1, Xavier Cathelineau1. 1. Department of Urology, L'Institut Mutualiste Montsouris, Paris, France. 2. Department of Urology, Faculdade de Medicina do ABC, Santo Andre, Brazil. 3. Department of Urology, L'Institut Mutualiste Montsouris, Paris, France. Petr.Macek@imm.fr. 4. Department of Urology, Hospital Israelita Albert Einstein, Sao Paulo, Brazil. 5. Faculty of Medicine in Rabigh, Department of Urology, King Abdulaziz University, Jeddah, Saudi Arabia. 6. Department of Urology, General University Hospital, Prague, Czech Republic. 7. Department of Pathology, L'Institut Mutualiste Montsouris, Paris, France.
Abstract
PURPOSE OF REVIEW: To compare laparoscopic partial nephrectomy (LPN) and robot-assisted partial nephrectomy (RAPN) performed in two European tertiary centers using the classic optimal surgical definition - "MIC" - and a new optimal surgical definition: the "Novel TRIFECTA" (NT) concept. We sought to strengthen the PN evidence and to test the NT's performance. RECENT FINDINGS: The study population comprehended 505 cases of localized kidney cancer from two tertiary centers between 2012 and 2019. The NT achievement was higher in the RAPN group when compared to LPN (70.5 vs. 87.4%; p = 0.004), while no differences were found when considering the MIC criteria. Also, a similar high-grade complications rate (Clavien-Dindo > III) and operative time (105 min vs. 100 min; p = NS) were found. In the multivariable regression, the RAPN approach was a predictor of NT achievement (OR 2.45; p = 0.008). NT achievement was higher in the RAPN group, while similar results were found when evaluating the MIC criteria. The NT definition could be more sensitive to the individual-specific responses related to the PN.
PURPOSE OF REVIEW: To compare laparoscopic partial nephrectomy (LPN) and robot-assisted partial nephrectomy (RAPN) performed in two European tertiary centers using the classic optimal surgical definition - "MIC" - and a new optimal surgical definition: the "Novel TRIFECTA" (NT) concept. We sought to strengthen the PN evidence and to test the NT's performance. RECENT FINDINGS: The study population comprehended 505 cases of localized kidney cancer from two tertiary centers between 2012 and 2019. The NT achievement was higher in the RAPN group when compared to LPN (70.5 vs. 87.4%; p = 0.004), while no differences were found when considering the MIC criteria. Also, a similar high-grade complications rate (Clavien-Dindo > III) and operative time (105 min vs. 100 min; p = NS) were found. In the multivariable regression, the RAPN approach was a predictor of NT achievement (OR 2.45; p = 0.008). NT achievement was higher in the RAPN group, while similar results were found when evaluating the MIC criteria. The NT definition could be more sensitive to the individual-specific responses related to the PN.