Seroprevalence of Legionella in Shanxi Province, China.

Using an ELISA with bacterial sonicate antigens, the prevalence of antibodies to the antigens of 15 legionellae was determined in 319 healthy individuals residing in Taiyuan, China (Shanxi Province). Significant antibody levels were detected to 11 antigens. Confirming earlier studies, an association was noted between cigarette smoking and seroreactivity, however, none was observed between occupation, or sex and seroreactivity. When the response to specific antigens or antigenic "groups" was studied, an association with work site was apparent. These data suggested a higher rate of exposure to Philadelphia 1 type antigens at the Bureau of Mining dormitory and a nearby electric power plant, and to E-327F/NY-23 type antigens at the Shanxi Mining College and Shanxi Daily newspaper. Further studies will define the reservoirs and mechanisms of exposure.