Literature DB >> 3402596

Stereotaxic injection of kainic acid into the striatum of rats induces synthesis of mRNA for heat shock protein 70.

J B Uney1, P N Leigh, C D Marsden, A Lees, B H Anderton.   

Abstract

Stereotaxic injection of the excitotoxin kainic acid into the striatum of rats has been shown to induce the production of messenger RNA to the 70 kDa heat shock protein. This was evident 2 h after injection and was maximal 24 h after injection of kainic acid. No change in the level of messenger RNA to beta-actin was detected.

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Year:  1988        PMID： 3402596     DOI： 10.1016/0014-5793(88)81265-1

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  4 in total

1.  Human homologues of the bacterial heat-shock protein DnaJ are preferentially expressed in neurons.

Authors:  M E Cheetham; J P Brion; B H Anderton
Journal:  Biochem J       Date:  1992-06-01       Impact factor: 3.857

2.  Time course of induction of a heat shock gene (hsp70) in the rabbit cerebellum after LSD in vivo: involvement of drug-induced hyperthermia.

Authors:  P Manzerra; I R Brown
Journal:  Neurochem Res       Date:  1990-01       Impact factor: 3.996

3.  Vascular heat shock protein expression in response to stress. Endocrine and autonomic regulation of this age-dependent response.

Authors:  R Udelsman; M J Blake; C A Stagg; D G Li; D J Putney; N J Holbrook
Journal:  J Clin Invest       Date:  1993-02       Impact factor: 14.808

Review 4.  Blockade of glutamate excitotoxicity and its clinical applications.

Authors:  K Hirose; P H Chan
Journal:  Neurochem Res       Date:  1993-04       Impact factor: 3.996
  4 in total

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