Gudrun Schneider1, Corinna Köhnke2, Henning Teismann3, Klaus Berger4. 1. Psychosomatic Medicine and Psychotherapy, Department for Mental Health, University Hospital Münster, Germany. Electronic address: Gudrun.Schneider@ukmuenster.de. 2. Institute of Epidemiology and Social Medicine, University of Münster, Germany. 3. Institute of Epidemiology and Social Medicine, University of Münster, Germany. Electronic address: Henning.Teismann@ukmuenster.de. 4. Institute of Epidemiology and Social Medicine, University of Münster, Germany. Electronic address: bergerk@uni-muenster.de.
Abstract
OBJECTIVE: Sociodemographic and lifestyle factors, childhood adversities, and personality aspects have been identified as contributing to the onset and course of depression. However, only few studies examined all aspects concomitantly in different populations. This was the objective of the study presented here. METHODS: The BiDirect Study includes three distinct cohorts: Cross-sectional data for 670 patients with depression (DEP), 283 patients with cardiovascular disease (CVD), and 787 population controls (POP) were available for the present analysis. Participants answered interviews and filled in questionnaires assessing depression details, childhood trauma, the Big Five personality traits, trait resilience as well as socioeconomic and lifestyle factors. Descriptive statistics and hierarchical linear regression analyses were employed to identify those factors, which contributed significantly to the explanation of depression severity scores (assessed by the Center for Epidemiologic Studies Depression Scale, CESD). RESULTS: In all three cohorts, the psychological variables explained most variance in depression scores (35-44%), while sociodemographic and lifestyle factors explained only very little variance (1-2%). When all postulated predictors were entered in the same regression model, higher neuroticism and lower resilience scores were associated with higher depression severity levels in all three cohorts, while higher childhood trauma proved significant in the cardiovascular and population cohort. CONCLUSION: Childhood trauma, neuroticism, and low resilience are significantly associated with depression in different populations. Although a considerable part of the variance in depression severity levels was explained by the variables studied here, more research on the impact of lifestyle and social factors on depression is needed.
OBJECTIVE: Sociodemographic and lifestyle factors, childhood adversities, and personality aspects have been identified as contributing to the onset and course of depression. However, only few studies examined all aspects concomitantly in different populations. This was the objective of the study presented here. METHODS: The BiDirect Study includes three distinct cohorts: Cross-sectional data for 670 patients with depression (DEP), 283 patients with cardiovascular disease (CVD), and 787 population controls (POP) were available for the present analysis. Participants answered interviews and filled in questionnaires assessing depression details, childhood trauma, the Big Five personality traits, trait resilience as well as socioeconomic and lifestyle factors. Descriptive statistics and hierarchical linear regression analyses were employed to identify those factors, which contributed significantly to the explanation of depression severity scores (assessed by the Center for Epidemiologic Studies Depression Scale, CESD). RESULTS: In all three cohorts, the psychological variables explained most variance in depression scores (35-44%), while sociodemographic and lifestyle factors explained only very little variance (1-2%). When all postulated predictors were entered in the same regression model, higher neuroticism and lower resilience scores were associated with higher depression severity levels in all three cohorts, while higher childhood trauma proved significant in the cardiovascular and population cohort. CONCLUSION: Childhood trauma, neuroticism, and low resilience are significantly associated with depression in different populations. Although a considerable part of the variance in depression severity levels was explained by the variables studied here, more research on the impact of lifestyle and social factors on depression is needed.
Authors: Melisa Chuong; Mark J Adams; Alex S F Kwong; Chris S Haley; Carmen Amador; Andrew M McIntosh Journal: JAMA Psychiatry Date: 2022-09-28 Impact factor: 25.911