The Role of Rare Earth Elements in Biodegradable Metals: A Review.

Compared with non-degradable metals, biodegradable metals, as a new generation of medical metallic materials, do not require secondary, which reduces the pain and economic burden of patients. However, currently developed biodegradable metals, including iron-based alloys, magnesium-based alloys, and zinc-based alloys, have deficiencies in their corrosion rates and mechanical properties, which have severely restricted the clinical application of biodegradable metals. So there is an urgent need to improve their mechanical properties, degradation behaviors and biocompatibility. Alloying is an important way to modify biodegradable metal materials. Rare earth elements (REEs) as alloying elements in biodegradable metals have attracted a great deal of attention due to their unique atomic structure and properties. The present review summarizes the effects of rare earth elements on the mechanical properties, degradation behaviors, and biocompatibility of biodegradable metals. Moreover, future research directions of rare earth elements alloying biodegradable metals are also prospected.