Romeo R Galang1, Suzanne M Newton1, Kate R Woodworth1, Isabel Griffin1, Titilope Oduyebo1, Christina L Sancken1, Emily O'Malley Olsen1, Kathryn Aveni2, Heather Wingate3, Hanna Shephard4, Chris Fussman5, Zahra S Alaali6, Kristin Silcox7, Samantha Siebman8, Umme-Aiman Halai9, Camille Delgado Lopez10, Mamie Lush11, Ayomide Sokale12, Jerusha Barton13, Ifrah Chaudhary14, Paul H Patrick15, Levi Schlosser16, Bethany Reynolds17, Nicole Gaarenstroom18, Sarah Chicchelly19, Jennifer S Read20,21, Leah de Wilde22, Deborah Mbotha23, Eduardo Azziz-Baumgartner1, Aron J Hall1, Van T Tong1, Sascha Ellington1, Suzanne M Gilboa1. 1. CDC COVID-19 Response, Centers for Disease Control and Prevention, Atlanta, Georgia, USA. 2. Division of Family Health Services, New Jersey Department of Health, Trenton, New Jersey, USA. 3. Communicable and Environmental Disease and Emergency Preparedness, Tennessee Department of Health, Nashville, Tennessee, USA. 4. Bureau of Family Health and Nutrition, Massachusetts Department of Public Health, Boston, Massachusetts, USA. 5. Maternal and Child Health Epidemiology Section, Michigan Department of Health and Human Services, Lansing, Michigan, USA. 6. Division of Epidemiology, New York State Department of Health, Albany, New York, USA. 7. Maternal and Child Health Bureau, Maryland Department of Health, Baltimore, Maryland, USA. 8. Emerging Infections Program, Minnesota Department of Health, St. Paul, Minnesota, USA. 9. Acute Communicable Disease Control Program, Los Angeles County Department of Public Health, Los Angeles, California, USA. 10. Division of Children with Special Medical Needs, Puerto Rico Department of Health, San Juan, Puerto Rico, Puerto Rico. 11. Division of Public Health, Nebraska Department of Health and Human Services, Lincoln, Nebraska, USA. 12. Division of Maternal, Child and Family Health, Philadelphia Department of Public Health, Philadelphia, Pennsylvania, USA. 13. Epidemiology Division, Georgia Department of Public Health, Atlanta, GA, USA. 14. Division of Disease Prevention and Control, Houston Health Department, Houston, Texas, USA. 15. Perinatal and Reproductive Health Division, Oklahoma State Department of Health, Oklahoma City, Oklahoma, USA. 16. Division of Disease Control, North Dakota Department of Health, Bismarck, North Dakota, USA. 17. Bureau of Epidemiology, Pennsylvania Department of Health, Pittsburgh, Pennsylvania, USA. 18. Nevada High Sierra Area Health Education Center, Reno, Nevada, USA. 19. Infectious Disease Epidemiology and Response, Kansas Department of Health and Environment, Topeka, Kansas, USA. 20. Infectious Disease Epidemiology, Vermont Department of Health, Burlington, Vermont, USA. 21. Larner College of Medicine, University of Vermont, Burlington, Vermont, USA. 22. Epidemiology Division, US Virgin Islands Department of Health, Christiansted, St. Croix, United States Virgin Islands. 23. Office of Communicable Disease Epidemiology, Washington State Department of Health, Shoreline, Washington, USA.
Abstract
BACKGROUND: Pregnant women with coronavirus disease 2019 (COVID-19) are at increased risk for severe illness compared with nonpregnant women. Data to assess risk factors for illness severity among pregnant women with COVID-19 are limited. This study aimed to determine risk factors associated with COVID-19 illness severity among pregnant women with SARS-CoV-2 infection. METHODS: Pregnant women with SARS-CoV-2 infection confirmed by molecular testing were reported during March 29, 2020-March 5, 2021 through the Surveillance for Emerging Threats to Mothers and Babies Network (SET-NET). Criteria for illness severity (asymptomatic, mild, moderate-to-severe, or critical) were adapted from National Institutes of Health and World Health Organization criteria. Crude and adjusted risk ratios for moderate-to-severe or critical COVID-19 illness were calculated for selected demographic and clinical characteristics. RESULTS: Among 7,950 pregnant women with SARS-CoV-2 infection, moderate-to-severe or critical COVID-19 illness was associated with age 25 years and older, healthcare occupation, pre-pregnancy obesity, chronic lung disease, chronic hypertension, and pregestational diabetes mellitus. Risk of moderate-to-severe or critical illness increased with the number of underlying medical or pregnancy-related conditions. CONCLUSIONS: Older age and having underlying medical conditions were associated with increased risk of moderate-to-severe or critical COVID-19 illness among pregnant women. This information might help pregnant women understand their risk for moderate-to-severe or critical COVID-19 illness and inform targeted public health messaging. Published by Oxford University Press for the Infectious Diseases Society of America 2021. This work is written by (a) US Government employee(s) and is in the public domain in the US.
BACKGROUND: Pregnant women with coronavirus disease 2019 (COVID-19) are at increased risk for severe illness compared with nonpregnant women. Data to assess risk factors for illness severity among pregnant women with COVID-19 are limited. This study aimed to determine risk factors associated with COVID-19 illness severity among pregnant women with SARS-CoV-2 infection. METHODS: Pregnant women with SARS-CoV-2 infection confirmed by molecular testing were reported during March 29, 2020-March 5, 2021 through the Surveillance for Emerging Threats to Mothers and Babies Network (SET-NET). Criteria for illness severity (asymptomatic, mild, moderate-to-severe, or critical) were adapted from National Institutes of Health and World Health Organization criteria. Crude and adjusted risk ratios for moderate-to-severe or critical COVID-19 illness were calculated for selected demographic and clinical characteristics. RESULTS: Among 7,950 pregnant women with SARS-CoV-2 infection, moderate-to-severe or critical COVID-19 illness was associated with age 25 years and older, healthcare occupation, pre-pregnancy obesity, chronic lung disease, chronic hypertension, and pregestational diabetes mellitus. Risk of moderate-to-severe or critical illness increased with the number of underlying medical or pregnancy-related conditions. CONCLUSIONS: Older age and having underlying medical conditions were associated with increased risk of moderate-to-severe or critical COVID-19 illness among pregnant women. This information might help pregnant women understand their risk for moderate-to-severe or critical COVID-19 illness and inform targeted public health messaging. Published by Oxford University Press for the Infectious Diseases Society of America 2021. This work is written by (a) US Government employee(s) and is in the public domain in the US.
Authors: César Pineda-Santoyo; Abraham Campos-Romero; Marco A Luna-Ruiz Esparza; Liliana E López-Luna; Martha E Sánchez-Zarate; Abraham Zepeda-González; Miguel A Fernández-Rojas; Jonathan Alcántar-Fernández Journal: Int J Environ Res Public Health Date: 2021-11-10 Impact factor: 3.390
Authors: Meghana A Limaye; Ashley S Roman; Megan E Trostle; Pooja Venkatesh; Meralis Lantigua Martinez; Sara G Brubaker; Judith Chervenak; Lili S Wei; Parita Sahani; Tracy B Grossman; Jessica A Meyer; Christina A Penfield Journal: J Matern Fetal Neonatal Med Date: 2021-09-01
Authors: Ernesto González-Mesa; Eduardo García-Fuentes; Rafael Carvia-Pontiasec; Ana I Lavado-Fernández; Celia Cuenca-Marín; María Suárez-Arana; Marta Blasco-Alonso; Blanca Benítez-Lara; Laura Mozas-Benítez; Ana González-Cazorla; Herink Egeberg-Neverdal; Jesús S Jiménez-López Journal: Diagnostics (Basel) Date: 2022-01-19