Erin Hetherington1, Sarah A Edwards2, Shannon E MacDonald2, Nicole Racine2, Sheri Madigan2, Sheila McDonald2, Suzanne Tough2. 1. Department of Obstetrics and Gynaecology (Hetherington), Cumming School of Medicine, University of Calgary, Calgary, Alta.; Department of Epidemiology, Biostatistics and Occupational Health (Hetherington), McGill University, Montréal, Que.; Department of Community Health Sciences (Edwards, Tough), Cumming School of Medicine, University of Calgary; Department of Pediatrics (MacDonald, McDonald, Tough), Cumming School of Medicine, University of Calgary; Faculty of Nursing (MacDonald), University of Alberta; Department of Psychology (Racine, Madigan, Tough), University of Calgary; Alberta Children's Hospital Research Institute (Racine, Madigan), Calgary, Alta. elhether@ucalgary.ca. 2. Department of Obstetrics and Gynaecology (Hetherington), Cumming School of Medicine, University of Calgary, Calgary, Alta.; Department of Epidemiology, Biostatistics and Occupational Health (Hetherington), McGill University, Montréal, Que.; Department of Community Health Sciences (Edwards, Tough), Cumming School of Medicine, University of Calgary; Department of Pediatrics (MacDonald, McDonald, Tough), Cumming School of Medicine, University of Calgary; Faculty of Nursing (MacDonald), University of Alberta; Department of Psychology (Racine, Madigan, Tough), University of Calgary; Alberta Children's Hospital Research Institute (Racine, Madigan), Calgary, Alta.
Abstract
BACKGROUND: Acceptance of a vaccine against SARS-CoV-2 is critical to achieving high levels of immunization. The objectives of this study were to understand mothers' SARS-CoV-2 vaccine intentions to explore reasons for and against SARS-CoV-2 vaccination. METHODS: Participants from the All Our Families pregnancy longitudinal cohort whose children had reached ages 9-12 years were invited in May-June 2020 to complete a survey on the impact of COVID-19. The survey covered topics about the impact of the pandemic and included 2 specific questions on mothers' intentions to vaccinate their child against SARS-CoV-2. Current responses were linked to previously collected data, including infant vaccine uptake. Multinomial regression models were run to estimate associations between demographic factors, past vaccination status and vaccination intention. Qualitative responses regarding factors affecting decision-making were analyzed thematically. RESULTS: The response rate was 53.8% (1321/2455). A minority of children of participants had partial or no vaccinations at age 2 (n = 200, 15.1%). A total of 60.4% of mothers (n = 798) intended to vaccinate their children with the SARS-CoV-2 vaccine, 8.6% (n = 113) did not intend to vaccinate and 31.0% (n = 410) were unsure. Lower education, lower income and incomplete vaccination history were inversely associated with intention to vaccinate. Thematic analysis of qualitative responses showed 10 themes, including safety and efficacy, long-term effects and a rushed process. INTERPRETATION: Within a cohort with historically high infant vaccination, a third of mothers remained unsure about vaccinating their children against SARS-CoV-2. Given the many uncertainties about future SARS-CoV-2 vaccines, clear communication regarding safety will be critical to ensuring vaccine uptake.
BACKGROUND: Acceptance of a vaccine against SARS-CoV-2 is critical to achieving high levels of immunization. The objectives of this study were to understand mothers' SARS-CoV-2 vaccine intentions to explore reasons for and against SARS-CoV-2 vaccination. METHODS:Participants from the All Our Families pregnancy longitudinal cohort whose children had reached ages 9-12 years were invited in May-June 2020 to complete a survey on the impact of COVID-19. The survey covered topics about the impact of the pandemic and included 2 specific questions on mothers' intentions to vaccinate their child against SARS-CoV-2. Current responses were linked to previously collected data, including infant vaccine uptake. Multinomial regression models were run to estimate associations between demographic factors, past vaccination status and vaccination intention. Qualitative responses regarding factors affecting decision-making were analyzed thematically. RESULTS: The response rate was 53.8% (1321/2455). A minority of children of participants had partial or no vaccinations at age 2 (n = 200, 15.1%). A total of 60.4% of mothers (n = 798) intended to vaccinate their children with the SARS-CoV-2 vaccine, 8.6% (n = 113) did not intend to vaccinate and 31.0% (n = 410) were unsure. Lower education, lower income and incomplete vaccination history were inversely associated with intention to vaccinate. Thematic analysis of qualitative responses showed 10 themes, including safety and efficacy, long-term effects and a rushed process. INTERPRETATION: Within a cohort with historically high infant vaccination, a third of mothers remained unsure about vaccinating their children against SARS-CoV-2. Given the many uncertainties about future SARS-CoV-2 vaccines, clear communication regarding safety will be critical to ensuring vaccine uptake.
Authors: Meagan E Miller; Mahvish Q Rahim; Scott L Coven; Seethal A Jacob; Gregory D Zimet; Carolyn G Meagher; Mary A Ott Journal: Hum Vaccin Immunother Date: 2022-03-28 Impact factor: 4.526
Authors: Gabriella Di Giuseppe; Concetta Paola Pelullo; Andrea Salvatore Volgare; Francesco Napolitano; Maria Pavia Journal: J Adolesc Health Date: 2022-01-19 Impact factor: 5.012