Literature DB >> 34019664

DeepGOWeb: fast and accurate protein function prediction on the (Semantic) Web.

Maxat Kulmanov1, Fernando Zhapa-Camacho1, Robert Hoehndorf1.   

Abstract

Understanding the functions of proteins is crucial to understand biological processes on a molecular level. Many more protein sequences are available than can be investigated experimentally. DeepGOPlus is a protein function prediction method based on deep learning and sequence similarity. DeepGOWeb makes the prediction model available through a website, an API, and through the SPARQL query language for interoperability with databases that rely on Semantic Web technologies. DeepGOWeb provides accurate and fast predictions and ensures that predicted functions are consistent with the Gene Ontology; it can provide predictions for any protein and any function in Gene Ontology. DeepGOWeb is freely available at https://deepgo.cbrc.kaust.edu.sa/.
© The Author(s) 2021. Published by Oxford University Press on behalf of Nucleic Acids Research.

Entities:  

Year:  2021        PMID: 34019664      PMCID: PMC8262746          DOI: 10.1093/nar/gkab373

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN: 0305-1048            Impact factor:   16.971


  27 in total

1.  Gene ontology: tool for the unification of biology. The Gene Ontology Consortium.

Authors:  M Ashburner; C A Ball; J A Blake; D Botstein; H Butler; J M Cherry; A P Davis; K Dolinski; S S Dwight; J T Eppig; M A Harris; D P Hill; L Issel-Tarver; A Kasarskis; S Lewis; J C Matese; J E Richardson; M Ringwald; G M Rubin; G Sherlock
Journal:  Nat Genet       Date:  2000-05       Impact factor: 38.330

2.  DEPICTER: Intrinsic Disorder and Disorder Function Prediction Server.

Authors:  Amita Barik; Akila Katuwawala; Jack Hanson; Kuldip Paliwal; Yaoqi Zhou; Lukasz Kurgan
Journal:  J Mol Biol       Date:  2019-12-21       Impact factor: 5.469

3.  Fast and sensitive protein alignment using DIAMOND.

Authors:  Benjamin Buchfink; Chao Xie; Daniel H Huson
Journal:  Nat Methods       Date:  2014-11-17       Impact factor: 28.547

4.  SIFTER search: a web server for accurate phylogeny-based protein function prediction.

Authors:  Sayed M Sahraeian; Kevin R Luo; Steven E Brenner
Journal:  Nucleic Acids Res       Date:  2015-05-15       Impact factor: 16.971

5.  NetGO: improving large-scale protein function prediction with massive network information.

Authors:  Ronghui You; Shuwei Yao; Yi Xiong; Xiaodi Huang; Fengzhu Sun; Hiroshi Mamitsuka; Shanfeng Zhu
Journal:  Nucleic Acids Res       Date:  2019-07-02       Impact factor: 16.971

Review 6.  Roles for text mining in protein function prediction.

Authors:  Karin M Verspoor
Journal:  Methods Mol Biol       Date:  2014

7.  FFPred 3: feature-based function prediction for all Gene Ontology domains.

Authors:  Domenico Cozzetto; Federico Minneci; Hannah Currant; David T Jones
Journal:  Sci Rep       Date:  2016-08-26       Impact factor: 4.379

8.  PredictProtein--an open resource for online prediction of protein structural and functional features.

Authors:  Guy Yachdav; Edda Kloppmann; Laszlo Kajan; Maximilian Hecht; Tatyana Goldberg; Tobias Hamp; Peter Hönigschmid; Andrea Schafferhans; Manfred Roos; Michael Bernhofer; Lothar Richter; Haim Ashkenazy; Marco Punta; Avner Schlessinger; Yana Bromberg; Reinhard Schneider; Gerrit Vriend; Chris Sander; Nir Ben-Tal; Burkhard Rost
Journal:  Nucleic Acids Res       Date:  2014-05-05       Impact factor: 16.971

9.  CATH: comprehensive structural and functional annotations for genome sequences.

Authors:  Ian Sillitoe; Tony E Lewis; Alison Cuff; Sayoni Das; Paul Ashford; Natalie L Dawson; Nicholas Furnham; Roman A Laskowski; David Lee; Jonathan G Lees; Sonja Lehtinen; Romain A Studer; Janet Thornton; Christine A Orengo
Journal:  Nucleic Acids Res       Date:  2014-10-27       Impact factor: 19.160

10.  Information-theoretic evaluation of predicted ontological annotations.

Authors:  Wyatt T Clark; Predrag Radivojac
Journal:  Bioinformatics       Date:  2013-07-01       Impact factor: 6.937

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