Literature DB >> 34019252

Inhibition of PI4KIIIα as a Novel Potential Approach for Gaucher Disease Treatment.

Linan Zheng1,2, Feng Hong3, Fude Huang4,5, Wenan Wang6,7.   

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Year:  2021        PMID： 34019252      PMCID： PMC8353038          DOI： 10.1007/s12264-021-00704-w

Source DB:  PubMed          Journal:  Neurosci Bull        ISSN： 1995-8218            Impact factor:   5.271


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  14 in total

1.  Pharmacological and genetic targeting of the PI4KA enzyme reveals its important role in maintaining plasma membrane phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate levels.

Authors:  Naveen Bojjireddy; Janos Botyanszki; Gerald Hammond; Donald Creech; Richard Peterson; Daniel C Kemp; Mark Snead; Randy Brown; Alastair Morrison; Steve Wilson; Steve Harrison; Chris Moore; Tamas Balla
Journal:  J Biol Chem       Date:  2014-01-10       Impact factor: 5.157

2.  Tau Accumulation and Defective Autophagy: A Common Pathological Mechanism Underlying Repeat-Expansion-Induced Neurodegenerative Diseases?

Authors:  Li Song; Luoying Zhang
Journal:  Neurosci Bull       Date:  2020-11-05       Impact factor: 5.203

3.  Inhibition of phosphatidylinositol kinase-III alpha induces or facilitates lysosome exocytosis from microglia.

Authors:  Shujing Mu; Nastasia K-H Lim; Fude Huang
Journal:  Neuroreport       Date:  2020-07-10       Impact factor: 1.837

Review 4.  Gaucher Disease: Clinical, Biological and Therapeutic Aspects.

Authors:  Azza Dandana; Souhaira Ben Khelifa; Hinda Chahed; Abdelhédi Miled; Salima Ferchichi
Journal:  Pathobiology       Date:  2015-11-21       Impact factor: 4.342

Review 5.  A Review of Gaucher Disease Pathophysiology, Clinical Presentation and Treatments.

Authors:  Jérôme Stirnemann; Nadia Belmatoug; Fabrice Camou; Christine Serratrice; Roseline Froissart; Catherine Caillaud; Thierry Levade; Leonardo Astudillo; Jacques Serratrice; Anaïs Brassier; Christian Rose; Thierry Billette de Villemeur; Marc G Berger
Journal:  Int J Mol Sci       Date:  2017-02-17       Impact factor: 5.923

6.  Neuroprotective Autophagic Flux Induced by Hyperbaric Oxygen Preconditioning is Mediated by Cystatin C.

Authors:  Zongping Fang; Yun Feng; Yuheng Li; Jiao Deng; Huang Nie; Qianzhi Yang; Shiquan Wang; Hailong Dong; Lize Xiong
Journal:  Neurosci Bull       Date:  2018-12-05       Impact factor: 5.203

Review 7.  Lysosomes as a therapeutic target.

Authors:  Srinivasa Reddy Bonam; Fengjuan Wang; Sylviane Muller
Journal:  Nat Rev Drug Discov       Date:  2019-09-02       Impact factor: 84.694

8.  mTOR hyperactivity mediates lysosomal dysfunction in Gaucher's disease iPSC-neuronal cells.

Authors:  Robert A Brown; Antanina Voit; Manasa P Srikanth; Julia A Thayer; Tami J Kingsbury; Marlene A Jacobson; Marta M Lipinski; Ricardo A Feldman; Ola Awad
Journal:  Dis Model Mech       Date:  2019-10-16       Impact factor: 5.758

9.  CNS-accessible Inhibitor of Glucosylceramide Synthase for Substrate Reduction Therapy of Neuronopathic Gaucher Disease.

Authors:  John Marshall; Ying Sun; Dinesh S Bangari; Eva Budman; Hyejung Park; Jennifer B Nietupski; Amy Allaire; Mary A Cromwell; Bing Wang; Gregory A Grabowski; John P Leonard; Seng H Cheng
Journal:  Mol Ther       Date:  2016-03-07       Impact factor: 11.454

Review 10.  Impairment of Lysosome Function and Autophagy in Rare Neurodegenerative Diseases.

Authors:  Frédéric Darios; Giovanni Stevanin
Journal:  J Mol Biol       Date:  2020-03-05       Impact factor: 5.469
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