Literature DB >> 34017030

Clinical characterization of respiratory large droplet production during common airway procedures using high-speed imaging.

S K Mueller1, R Veltrup2, B Jakubaß2, S Kniesburges2, M J Huebner3, J S Kempfle4, S Dittrich3, H Iro5, M Döllinger2.   

Abstract

During the COVID-19 pandemic, a significant number of healthcare workers have been infected with SARS-CoV-2. However, there remains little knowledge regarding large droplet dissemination during airway management procedures in real life settings. 12 different airway management procedures were investigated during routine clinical care. A high-speed video camera (1000 frames/second) was for imaging. Quantitative droplet characteristics as size, distance traveled, and velocity were computed. Droplets were detected in 8/12 procedures. The droplet trajectories could be divided into two distinctive patterns (type 1/2). Type 1 represented a ballistic trajectory with higher speed large droplets whereas type 2 represented a random trajectory of slower particles that persisted longer in air. The use of tracheal cannula filters reduced the amount of droplets. Respiratory droplet patterns generated during airway management procedures follow two distinctive trajectories based on the influence of aerodynamic forces. Speaking and coughing produce more droplets than non-invasive ventilation therapy confirming these behaviors as exposure risks. Even large droplets may exhibit patterns resembling the fluid dynamics smaller airborne aerosols that follow the airflow convectively and may place the healthcare provider at risk.

Entities:  

Year:  2021        PMID: 34017030     DOI: 10.1038/s41598-021-89760-w

Source DB:  PubMed          Journal:  Sci Rep        ISSN: 2045-2322            Impact factor:   4.379


  2 in total

1.  Coronavirus Disease 2019 Patients in Earlier Stages Exhaled Millions of Severe Acute Respiratory Syndrome Coronavirus 2 Per Hour.

Authors:  Jianxin Ma; Xiao Qi; Haoxuan Chen; Xinyue Li; Zheng Zhang; Haibin Wang; Lingli Sun; Lu Zhang; Jiazhen Guo; Lidia Morawska; Sergey A Grinshpun; Pratim Biswas; Richard C Flagan; Maosheng Yao
Journal:  Clin Infect Dis       Date:  2021-05-18       Impact factor: 9.079

2.  Community Transmission of Severe Acute Respiratory Syndrome Coronavirus 2, Shenzhen, China, 2020.

Authors:  Jiaye Liu; Xuejiao Liao; Shen Qian; Jing Yuan; Fuxiang Wang; Yingxia Liu; Zhaoqin Wang; Fu-Sheng Wang; Lei Liu; Zheng Zhang
Journal:  Emerg Infect Dis       Date:  2020-06-17       Impact factor: 6.883

  2 in total
  3 in total

1.  Risk of Transmitting Coronavirus Disease 2019 During Nebulizer Treatment: A Systematic Review.

Authors:  Karen M Goldstein; Kamrouz Ghadimi; Harry Mystakelis; Yuanyuan Kong; Tongtong Meng; Sarah Cantrell; Megan Von Isenburg; Adelaide Gordon; Belinda Ear; Jennifer M Gierisch; John W Williams
Journal:  J Aerosol Med Pulm Drug Deliv       Date:  2021-04-21       Impact factor: 3.440

2.  Inhaled hydrogel-based microspheres for management of COVID-19: A new sweeper biological platform.

Authors:  Ruoyu Cheng; Hélder A Santos
Journal:  Matter       Date:  2022-04-06

3.  Evaluation of Respiratory Particle Emission during Otorhinolaryngological Procedures in the Context of the SARS-CoV-2 Pandemic.

Authors:  Reinhard Veltrup; Stefan Kniesburges; Michael Döllinger; Sebastian Falk; Sarina K Mueller
Journal:  Diagnostics (Basel)       Date:  2022-06-30
  3 in total

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