Literature DB >> 3401296

MR imaging of rat brain glioma: Gd-DTPA versus Gd-DOTA.

V M Runge1, S Jacobson, M L Wood, D Kaufman, L S Adelman.   

Abstract

The enhancement properties of gadolinium diethylenetriaminepentaacetic acid (DTPA) and gadolinium tetraazacyclododecanetetraacetic acid (DOTA) were compared using a rat glioma model. In vitro analysis included the calculation of T1 relaxivity and determination of characteristic curves. Enhancement of the intracerebral glioma was studied in 23 rats approximately 2 weeks after glioma implantation with Gd-DTPA in 12 rats and Gd-DOTA in 11 rats. Six rats were also studied 1 week after implantation. Gd-DTPA exhibited a slightly greater T1 relaxivity in vitro than Gd-DOTA. Enhancement of the glioma was also greater with Gd-DTPA than with Gd-DOTA (P less than .05).

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 3401296     DOI： 10.1148/radiology.166.3.3401296

Source DB:  PubMed          Journal:  Radiology        ISSN： 0033-8419            Impact factor:   11.105


  10 in total

1.  Evaluation of [¹¹¹In]-labeled zinc-dipicolylamine tracers for SPECT imaging of bacterial infection.

Authors:  Douglas R Rice; Adam J Plaunt; Serhan Turkyilmaz; Miles Smith; Yuzhen Wang; Mary Rusckowski; Bradley D Smith
Journal:  Mol Imaging Biol       Date:  2015-04       Impact factor: 3.488

2.  Sequential imaging and volumetric analysis of an intracerebral C6 glioma by means of a clinical MRI system.

Authors:  F A Raila; A P Bowles; E Perkins; A Terrell
Journal:  J Neurooncol       Date:  1999-05       Impact factor: 4.130

3.  Noninvasive monitoring of tumor growth in a rat glioma model: comparison between neurological assessment and animal imaging.

Authors:  Ting-Chung Wang; Ing-Tsung Hsiao; Yu-Kai Cheng; Shiaw-Pyng Wey; Tzu-Chen Yen; Kun-Ju Lin
Journal:  J Neurooncol       Date:  2011-02-12       Impact factor: 4.130

4.  Preparation, characterization and in vivo assessment of Gd-albumin and Gd-dendrimer conjugates as intravascular contrast-enhancing agents for MRI.

Authors:  Kido Nwe; Diane Milenic; L Henry Bryant; Celeste A S Regino; Martin W Brechbiel
Journal:  J Inorg Biochem       Date:  2011-04-02       Impact factor: 4.155

5.  Magnetic resonance imaging of the pancreas in streptozotocin-induced diabetic rats: Gadofluorine P and Gd-DOTA.

Authors:  Hye Rim Cho; Youkyung Lee; Philip Doble; David Bishop; Dominic Hare; Young-Jae Kim; Kwang Gi Kim; Hye Seung Jung; Kyong Soo Park; Seung Hong Choi; Woo Kyung Moon
Journal:  World J Gastroenterol       Date:  2015-05-21       Impact factor: 5.742

6.  Comparison of MRI properties between derivatized DTPA and DOTA gadolinium-dendrimer conjugates.

Authors:  K Nwe; M Bernardo; C A S Regino; M Williams; M W Brechbiel
Journal:  Bioorg Med Chem       Date:  2010-07-08       Impact factor: 3.641

7.  MRI assessment of experimental gliomas using 17.6 T.

Authors:  Marc A Schwarz; Mirko Pham; Xavier Helluy; Arnd Doerfler; Tobias Engelhorn
Journal:  Neuroradiology       Date:  2013-03-10       Impact factor: 2.804

8.  Differential permeability and quantitative MR imaging of a human lung carcinoma brain xenograft in the nude rat.

Authors:  P A Barnett; S Roman-Goldstein; F Ramsey; C I McCormick; G Sexton; J Szumowski; E A Neuwelt
Journal:  Am J Pathol       Date:  1995-02       Impact factor: 4.307

9.  MR imaging of experimental meningeal melanomatosis in nude rats.

Authors:  J Martos; D Petersen; U Klose; H Requardt; R Buchholz; P Ohneseit; M Schabet; K Voigt
Journal:  J Neurooncol       Date:  1992-11       Impact factor: 4.130

Review 10.  Progress on the diagnosis and evaluation of brain tumors.

Authors:  Huile Gao; Xinguo Jiang
Journal:  Cancer Imaging       Date:  2013-12-11       Impact factor: 3.909
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.