Literature DB >> 3400818

A new quantitative spectrophotometric assay of ischemia-reperfusion injury in skeletal muscle.

M Belkin1, R D Brown, J G Wright, W W LaMorte, R W Hobson.   

Abstract

Characterization of ischemia-reperfusion injury of skeletal muscle remains poorly defined. A new quantitative assay to measure ischemic skeletal muscle injury is described and validated in a rat hindlimb model. This biochemical spectrophotometric technique measures triphenyltetrazolium chloride reduction in ischemic muscle. The reduction assay demonstrated significant injury after 3 hours of ischemia (25.4 +/- 9.7 percent of control activity; p less than 0.05). More severe injury occurred after 4 or more hours (less than 3 percent of control activity; p less than 0.05). This assay is an objective and quantitative method for characterizing ischemia-reperfusion injury.

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Year:  1988        PMID： 3400818     DOI： 10.1016/s0002-9610(88)80360-x

Source DB:  PubMed          Journal:  Am J Surg        ISSN： 0002-9610            Impact factor:   2.565


  17 in total

1.  Microvascular perfusion and intramuscular temperature of the calf during cooling.

Authors:  Noelle M Selkow; Carly Day; Zhenqi Liu; Joseph M Hart; Jay Hertel; Susan A Saliba
Journal:  Med Sci Sports Exerc       Date:  2012-05       Impact factor: 5.411

2.  Overexpression of endothelial nitric oxide synthase in endothelial cells is protective against ischemia-reperfusion injury in mouse skeletal muscle.

Authors:  Masanori Ozaki; Seinosuke Kawashima; Tetsuaki Hirase; Tomoya Yamashita; Masayuki Namiki; Nobutaka Inoue; Ken-ichi Hirata Ki; Mitsuhiro Yokoyama
Journal:  Am J Pathol       Date:  2002-04       Impact factor: 4.307

3.  Blood flow after exercise-induced muscle damage.

Authors:  Noelle M Selkow; Daniel C Herman; Zhenqi Liu; Jay Hertel; Joseph M Hart; Susan A Saliba
Journal:  J Athl Train       Date:  2015-02-06       Impact factor: 2.860

4.  Alterations of biochemical marker levels and myonuclear numbers in rat skeletal muscle after ischemia-reperfusion.

Authors:  Motoharu Itoh; Noriaki Shimokawa; Yuki Tajika; Tohru Murakami; Nobutaka Aotsuka; Ronny Lesmana; Reni Farenia; Toshiharu Iwasaki; Junichi Okda; Hiroshi Yorifuji; Noriyuki Koibuchi
Journal:  Mol Cell Biochem       Date:  2012-10-13       Impact factor: 3.396

5.  Secondary injury after musculoskeletal trauma: a review and update.

Authors:  Mark A Merrick
Journal:  J Athl Train       Date:  2002-04       Impact factor: 2.860

6.  Experimental models to study microcirculatory dysfunction in muscle ischemia-reperfusion and osteomyocutaneous flap transfer.

Authors:  Michael D Menger; Matthias W Laschke; Michaela Amon; Rene Schramm; Henrik Thorlacius; Martin Rücker; Brigitte Vollmar
Journal:  Langenbecks Arch Surg       Date:  2003-10-07       Impact factor: 3.445

7.  Administration of exogenous adenosine triphosphate to ischemic skeletal muscle induces an energy-sparing effect: role of adenosine receptors.

Authors:  Claudio Maldonado; Sathnur B Pushpakumar; Gustavo Perez-Abadia; Sengodagounder Arumugam; Andrew N Lane
Journal:  J Surg Res       Date:  2012-07-06       Impact factor: 2.192

Review 8.  Chronology of mitochondrial and cellular events during skeletal muscle ischemia-reperfusion.

Authors:  Stéphanie Paradis; Anne-Laure Charles; Alain Meyer; Anne Lejay; James W Scholey; Nabil Chakfé; Joffrey Zoll; Bernard Geny
Journal:  Am J Physiol Cell Physiol       Date:  2016-04-13       Impact factor: 4.249

9.  Toll-like receptors in ischaemia and its potential role in the pathophysiology of muscle damage in critical limb ischaemia.

Authors:  Hemanshu Patel; Sidney G Shaw; Xu Shi-Wen; David Abraham; Daryll M Baker; Janice C S Tsui
Journal:  Cardiol Res Pract       Date:  2012-02-07       Impact factor: 1.866

10.  Effects of ischaemia and post-ischaemic reperfusion on the passive and active electrical parameters of rat skeletal muscle fibres.

Authors:  D Tricarico; D C Camerino
Journal:  Pflugers Arch       Date:  1994-01       Impact factor: 3.657
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