| Literature DB >> 34007998 |
Francesco Paolo Bianchi1, Cinzia Annatea Germinario1, Giovanni Migliore2, Luigi Vimercati3, Andrea Martinelli1, Annamaria Lobifaro1, Silvio Tafuri1, Pasquale Stefanizzi1.
Abstract
In the preregistration trial, data on efficacy of BNT162b2 mRNA vaccine against SARS-CoV-2 infection were not collected. This study aimed to evaluate vaccine effectiveness (VE) against documented infection. Bari Policlinico University Hospital health care workers (HCWs) who completed the vaccination schedule were matched with HCWs who had refused vaccination. VE for documented infection was 61.9% (95% confidence interval [CI], 19.2%-82.0%) 14-20 days after first dose, 87.9% (95% CI, 51.7%-97.0%) 21-27 days after first dose, and 96.0% (95% CI, 82.2%-99.1%) 7 or more days after second dose. Unvaccinated HCWs remain a concern in the context of the pandemic emergency.Entities:
Keywords: COVID-19; documented infection; healthcare workers; vaccine effectiveness
Year: 2021 PMID: 34007998 PMCID: PMC8194590 DOI: 10.1093/infdis/jiab262
Source DB: PubMed Journal: J Infect Dis ISSN: 0022-1899 Impact factor: 5.226