Literature DB >> 34006956

Transformation of microbiology data into a standardised data representation using OpenEHR.

Antje Wulff1, Claas Baier2, Michael Marschollek3, Simone Scheithauer4, Sarah Ballout3, Erik Tute3, Kim Katrin Sommer3, Martin Kaase4, Anneka Sargeant5, Cora Drenkhahn6, Dirk Schlüter7.   

Abstract

The spread of multidrug resistant organisms (MDRO) is a global healthcare challenge. Nosocomial outbreaks caused by MDRO are an important contributor to this threat. Computer-based applications facilitating outbreak detection can be essential to address this issue. To allow application reusability across institutions, the various heterogeneous microbiology data representations needs to be transformed into standardised, unambiguous data models. In this work, we present a multi-centric standardisation approach by using openEHR as modelling standard. Data models have been consented in a multicentre and international approach. Participating sites integrated microbiology reports from primary source systems into an openEHR-based data platform. For evaluation, we implemented a prototypical application, compared the transformed data with original reports and conducted automated data quality checks. We were able to develop standardised and interoperable microbiology data models. The publicly available data models can be used across institutions to transform real-life microbiology reports into standardised representations. The implementation of a proof-of-principle and quality control application demonstrated that the new formats as well as the integration processes are feasible. Holistic transformation of microbiological data into standardised openEHR based formats is feasible in a real-life multicentre setting and lays the foundation for developing cross-institutional, automated outbreak detection systems.

Entities:  

Year:  2021        PMID: 34006956     DOI: 10.1038/s41598-021-89796-y

Source DB:  PubMed          Journal:  Sci Rep        ISSN: 2045-2322            Impact factor:   4.379


  4 in total

1.  Early Detection of Infection Chains & Outbreaks: Use Case Infection Control.

Authors:  A Sargeant; T von Landesberger; C Baier; F Bange; A Dalpke; T Eckmanns; S Glöckner; M Kaase; G Krause; M Marschollek; B Malone; M Niepert; S Rey; A Wulff; S Scheithauer
Journal:  Stud Health Technol Inform       Date:  2019

2.  A Report on Archetype Modelling in a Nationwide Data Infrastructure Project.

Authors:  Antje Wulff; Kim Katrin Sommer; Sarah Ballout; Birger Haarbrandt; Matthias Gietzelt
Journal:  Stud Health Technol Inform       Date:  2019

3.  Clinical Knowledge Governance Framework for Nationwide Data Infrastructure Projects.

Authors:  Antje Wulff; Birger Haarbrandt; Michael Marschollek
Journal:  Stud Health Technol Inform       Date:  2018

4.  Colistin Resistance in Carbapenem-Resistant Klebsiella pneumoniae: Laboratory Detection and Impact on Mortality.

Authors:  Laura J Rojas; Madiha Salim; Eric Cober; Sandra S Richter; Federico Perez; Robert A Salata; Robert C Kalayjian; Richard R Watkins; Steve Marshall; Susan D Rudin; T Nicholas Domitrovic; Andrea M Hujer; Kristine M Hujer; Yohei Doi; Keith S Kaye; Scott Evans; Vance G Fowler; Robert A Bonomo; David van Duin
Journal:  Clin Infect Dis       Date:  2017-03-15       Impact factor: 9.079

  4 in total
  2 in total

Review 1.  Electronic Health Record Network Research in Infectious Diseases.

Authors:  Ravi Jhaveri; Jordan John; Marc Rosenman
Journal:  Clin Ther       Date:  2021-10-08       Impact factor: 3.393

2.  Interpretable Clinical Decision Support System for Audiology Based on Predicted Common Audiological Functional Parameters (CAFPAs).

Authors:  Mareike Buhl
Journal:  Diagnostics (Basel)       Date:  2022-02-11
  2 in total

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