Xiang Feng1, Lina Zhang2, Yanling Tan3, Aihua Feng4, Fei Luo4, Mengfan Xu4, Hong Ye4, Hongyu Zhu4, Peng Zhou2, Hua Li4. 1. Department of Gynaecology and Obstetrics, The First College of Clinical Medical Science, Three Gorges University, YiChang, 443000, China. fengxiang198888@126.com. 2. State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, 214122, China. 3. Department of Orthopedics, The First Hospital of YiChang, YiChang, 443000, China. 4. Department of Gynaecology and Obstetrics, The First College of Clinical Medical Science, Three Gorges University, YiChang, 443000, China.
Abstract
BACKGROUND: Primitive neuroectodermal tumor (PNET) is a relatively rare malignant small round cell tumor, and the occurrence of cervical PNET during pregnancy is extremely rare. CASE PRESENTATION: A case of pregnancy complicated by PNET at our hospital was reported. A 19-year-old pregnant woman presented to the hospital due to multiple instances of vaginal bleeding during the first and second trimesters. She was initially considered for threatened abortion but was ultimately diagnosed with cervical PNET. No standard treatment plan has been developed for pregnant women with this tumor. After completing the necessary examinations, doctors cooperated with the patient and her family to develop a surgical treatment plan. The patient recovered well after surgery, but she refused radiotherapy and chemotherapy. After nearly 3 years of follow-up visits, the patient is alive with no signs of recurrence. CONCLUSIONS: PNET during pregnancy is a rare but complex condition. It is necessary to devise an individualized treatment plan according to gestational age. Timely surgical treatment can significantly prolong the survival time of patients but may also lead to fetal loss and the inability to carry a pregnancy.
BACKGROUND:Primitive neuroectodermal tumor (PNET) is a relatively rare malignant small round cell tumor, and the occurrence of cervical PNET during pregnancy is extremely rare. CASE PRESENTATION: A case of pregnancy complicated by PNET at our hospital was reported. A 19-year-old pregnant woman presented to the hospital due to multiple instances of vaginal bleeding during the first and second trimesters. She was initially considered for threatened abortion but was ultimately diagnosed with cervical PNET. No standard treatment plan has been developed for pregnant women with this tumor. After completing the necessary examinations, doctors cooperated with the patient and her family to develop a surgical treatment plan. The patient recovered well after surgery, but she refused radiotherapy and chemotherapy. After nearly 3 years of follow-up visits, the patient is alive with no signs of recurrence. CONCLUSIONS: PNET during pregnancy is a rare but complex condition. It is necessary to devise an individualized treatment plan according to gestational age. Timely surgical treatment can significantly prolong the survival time of patients but may also lead to fetal loss and the inability to carry a pregnancy.
Authors: P Pauwels; P Ambros; C Hattinger; M Lammens; P Dal Cin; J Ribot; A Struyk; H van den Berghe Journal: Virchows Arch Date: 2000-01 Impact factor: 4.064