Anne-Laure Couderc1,2,3, Stéphanie Gentile4, Emilie Nouguerède5,6, Françoise Celerien7, Zoulikha Moussaoui7, Dominique Rey5,6, Fabrice Barlesi8,9, Pascal-Alexandre Thomas9,10, Laurent Greillier9,11, Patrick Villani5,6,12. 1. Internal Medicine, Geriatrics and Therapeutic Unit, Marseille University Hospital (AP-HM), 270 Boulevard de Sainte Marguerite, 13009, Marseille, France. anne-laure.couderc@ap-hm.fr. 2. Coordination Unit for Geriatric Oncology (UCOG), PACA West, Marseille, France. anne-laure.couderc@ap-hm.fr. 3. Aix-Marseille University, CNRS, EFS, ADES, Marseille, France. anne-laure.couderc@ap-hm.fr. 4. Public Health Department, Aix-Marseille University, Marseille, France. 5. Internal Medicine, Geriatrics and Therapeutic Unit, Marseille University Hospital (AP-HM), 270 Boulevard de Sainte Marguerite, 13009, Marseille, France. 6. Coordination Unit for Geriatric Oncology (UCOG), PACA West, Marseille, France. 7. Cancerology Coordination Centre, Marseille, France. 8. Gustave Roussy Cancer Campus, Villejuif, France. 9. Aix-Marseille University, CNRS, INSERM, CRCM, Marseille, France. 10. Thoracic Surgery Unit, AP-HM, Marseille, France. 11. Multidisciplinary Oncology and Therapeutic Innovations Department, AP-HM, Marseille, France. 12. Aix-Marseille University, CNRS, EFS, ADES, Marseille, France.
Abstract
PURPOSE: Assessment of vulnerability with the G8 screening tool according to cancer localization and weight of the G8 items when screening frailty in thoracic and lung cancer (TLC) compared to other cancer localizations. METHODS: This study was conducted retrospectively on all G8 data collected for older cancer patients between April 2015 and December 2019 at Marseille University Hospital. RESULTS: One thousand four hundred and thirty-one patients were included; the median age was 80.6 years and 62.3% of the patients were men. The most common type of cancer was thoracic cancer (34.5%). A majority of patients with thoracic cancers (74.4%) had an impaired G8. In a logistic regression model, male gender, age < 80 years, BMI < 23 kg/m2, normal psychological status, and health status perception were independent factors associated with thoracic cancers. CONCLUSION: Improving nutritional status and maintaining mental health are important issues to consider before treatment initiation in older patients with thoracic cancers.
PURPOSE: Assessment of vulnerability with the G8 screening tool according to cancer localization and weight of the G8 items when screening frailty in thoracic and lung cancer (TLC) compared to other cancer localizations. METHODS: This study was conducted retrospectively on all G8 data collected for older cancer patients between April 2015 and December 2019 at Marseille University Hospital. RESULTS: One thousand four hundred and thirty-one patients were included; the median age was 80.6 years and 62.3% of the patients were men. The most common type of cancer was thoracic cancer (34.5%). A majority of patients with thoracic cancers (74.4%) had an impaired G8. In a logistic regression model, male gender, age < 80 years, BMI < 23 kg/m2, normal psychological status, and health status perception were independent factors associated with thoracic cancers. CONCLUSION: Improving nutritional status and maintaining mental health are important issues to consider before treatment initiation in older patients with thoracic cancers.