Bangrong Song1, Haiming Dang1, Ran Dong2. 1. Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, No.2 Anzhen Road, Chaoyang, Beijing, 100029, China. 2. Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, No.2 Anzhen Road, Chaoyang, Beijing, 100029, China. randong03@yeah.net.
Abstract
BACKGROUND: It's necessary to analyze the related risk factors and complications of low cardiac output syndrome (LCOS) after operation in children with congenital heart disease (CHD), to elucidate the management strategy of LCOS. METHODS: CHD children admitted to the department of cardiology in our hospital from January 15, 2019 to October 31, 2020 were included. The personal and clinical data of CHD children with LCOS and without LCOS were collected and compared. Logistic regression analyses were conducted to identify the risk factors of postoperative LCOS. Besides, the complication and mortality of LCOS and no LCOS patients were compared. RESULTS: A total of 283 CHD patients were included, the incidence of postoperative LCOS in CHD patients was 12.37%. There were significant differences in the age, preoperative oxygen saturation, two-way ventricular shunt, duration of CPB and postoperative residual shunt between two groups (all p < 0.05). Logistic regression analyses indicated that age ≤ 4y(OR2.426, 95%CI1.044 ~ 4.149), preoperative oxygen saturation ≤ 93%(OR2.175, 95%CI1.182 ~ 5.033), two-way ventricular shunt (OR3.994, 95%CI1.247 ~ 6.797), duration of CPB ≥ 60 min(OR2.172, 95%CI1.002 ~ 4.309), postoperative residual shunt (OR1.487, 95%CI1.093 ~ 2.383) were the independent risk factors of LCOS in patients with CHD (all p < 0.05). There were significant differences in the acute liver injury, acute kidney injury, pulmonary infection, tracheotomy, duration of mechanical ventilation, length of ICU stay and mortality (all p < 0.05), no significant difference in the 24 h drainage was found(p = 0.095). CONCLUSION: LCOS after CHD is common, more attentions should be paid to those patients with age ≤ 4y, preoperative oxygen saturation ≤ 93%, two-way ventricular shunt, duration of CPB ≥ 60 min, postoperative residual shunt to improve the prognosis of CHD patients.
BACKGROUND: It's necessary to analyze the related risk factors and complications of low cardiac output syndrome (LCOS) after operation in children with congenital heart disease (CHD), to elucidate the management strategy of LCOS. METHODS: CHD children admitted to the department of cardiology in our hospital from January 15, 2019 to October 31, 2020 were included. The personal and clinical data of CHD children with LCOS and without LCOS were collected and compared. Logistic regression analyses were conducted to identify the risk factors of postoperative LCOS. Besides, the complication and mortality of LCOS and no LCOS patients were compared. RESULTS: A total of 283 CHD patients were included, the incidence of postoperative LCOS in CHD patients was 12.37%. There were significant differences in the age, preoperative oxygen saturation, two-way ventricular shunt, duration of CPB and postoperative residual shunt between two groups (all p < 0.05). Logistic regression analyses indicated that age ≤ 4y(OR2.426, 95%CI1.044 ~ 4.149), preoperative oxygen saturation ≤ 93%(OR2.175, 95%CI1.182 ~ 5.033), two-way ventricular shunt (OR3.994, 95%CI1.247 ~ 6.797), duration of CPB ≥ 60 min(OR2.172, 95%CI1.002 ~ 4.309), postoperative residual shunt (OR1.487, 95%CI1.093 ~ 2.383) were the independent risk factors of LCOS in patients with CHD (all p < 0.05). There were significant differences in the acute liver injury, acute kidney injury, pulmonary infection, tracheotomy, duration of mechanical ventilation, length of ICU stay and mortality (all p < 0.05), no significant difference in the 24 h drainage was found(p = 0.095). CONCLUSION: LCOS after CHD is common, more attentions should be paid to those patients with age ≤ 4y, preoperative oxygen saturation ≤ 93%, two-way ventricular shunt, duration of CPB ≥ 60 min, postoperative residual shunt to improve the prognosis of CHD patients.
Authors: Alexander C Egbe; Rahul Vojjini; Mohamed Badawy; Vaibhav Jain; Crystal R Bonnichsen; Yogesh N V Reddy; Masaru Obokata; Barry A Borlaug Journal: Can J Cardiol Date: 2020-02-26 Impact factor: 5.223
Authors: Eva M Marwali; Putri Caesa; Muhammad Rayhan; Poppy S Roebiono; Dicky Fakhri; Nikolaus A Haas; Masaki Kajimoto; Michael A Portman Journal: Cardiol Young Date: 2020-11-10 Impact factor: 1.093
Authors: Vladimir V Lomivorotov; Sergey M Efremov; Mikhail Y Kirov; Evgeny V Fominskiy; Alexander M Karaskov Journal: J Cardiothorac Vasc Anesth Date: 2016-07-29 Impact factor: 2.628
Authors: Helmut Baumgartner; Julie De Backer; Sonya V Babu-Narayan; Werner Budts; Massimo Chessa; Gerhard-Paul Diller; Bernard Lung; Jolanda Kluin; Irene M Lang; Folkert Meijboom; Philip Moons; Barbara J M Mulder; Erwin Oechslin; Jolien W Roos-Hesselink; Markus Schwerzmann; Lars Sondergaard; Katja Zeppenfeld Journal: Eur Heart J Date: 2021-02-11 Impact factor: 29.983
Authors: Darlene Huisenga; Sacha La Bastide-Van Gemert; Andrew Van Bergen; Jane Sweeney; Mijna Hadders-Algra Journal: Dev Med Child Neurol Date: 2020-03-09 Impact factor: 5.449
Authors: Uri Pollak; Hai Zemmour; Elior Shaked; Judith Magenheim; Ori Fridlich; Amit Korach; Alain E Serraf; David Mishaly; Benjamin Glaser; Ruth Shemer; Yuval Dor Journal: J Cardiovasc Transl Res Date: 2022-08-17 Impact factor: 3.216