Takeshi Inoue1,2, Ryoko Otani3, Toshiyuki Iguchi4, Ryuta Ishii5, Soh Uchida6, Ayumi Okada7, Shinji Kitayama8, Kenshi Koyanagi9, Yuki Suzuki10, Yuichi Suzuki11, Yoshino Sumi12, Shizuo Takamiya13,14, Yasuko Tsurumaru15, Shinichiro Nagamitsu5, Yoshimitsu Fukai16, Chikako Fujii15, Michiko Matsuoka17, Junpei Iwanami3, Akio Wakabayashi18, Ryoichi Sakuta3. 1. Dokkyo Medical University Saitama Medical Center, Child Development and Psychosomatic Medicine Center, 2-1-50, Minami-Koshigaya, Koshigaya-shi, Saitama-Ken, 343-8555, Japan. tinoue0123@gmail.com. 2. Department of Pediatrics, Dokkyo Medical University Saitama Medical Center, Saitama, Japan. tinoue0123@gmail.com. 3. Dokkyo Medical University Saitama Medical Center, Child Development and Psychosomatic Medicine Center, 2-1-50, Minami-Koshigaya, Koshigaya-shi, Saitama-Ken, 343-8555, Japan. 4. Department of Pediatrics, Hoshigaoka Maternity Hospital, Aichi, Japan. 5. Department of Pediatrics and Child health, Kurume University School of Medicine, Fukuoka, Japan. 6. Department of Pediatrics, Tachikawa Hospital, Tokyo, Japan. 7. Department of Pediatrics, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan. 8. Himeji City Center for the Disabled, Hyogo, Japan. 9. Nagasaki Prefectural Center of Medicine and Welfare for Children, Nagasaki, Japan. 10. Department of Pediatrics, National Hospital Organization Mie National Hospital, Mie, Japan. 11. Department of Pediatrics, Fukushima Medical University School of Medicine, Fukushima, Japan. 12. Mental and developmental clinic for children "Elm Tree", Hokaido, Japan. 13. Psychiatry Department, Kobe City Nishi-Kobe Medical Center, Hyogo, Japan. 14. Takamiya Psychiatry Clinic, Hyogo, Japan. 15. Department of Pediatrics, Okayama University Hospital, Okayama, Japan. 16. Tokyo Metropolitan Children's Medical Center, Psychosomatic Medicine, Tokyo, Japan. 17. Department of Neuropsychiatry, Kurume University School of Medicine, Fukuoka, Japan. 18. Department of Psychology, Chiba University, Chiba, Japan.
Abstract
BACKGROUND: Autism spectrum disorder (ASD) and feeding and eating disorders (FEDs) such as anorexia nervosa (AN) are strongly linked as evidenced by frequent comorbidity and overlapping traits. However, eating and social behaviors are shaped by culture, so it is critical to examine these associations in different populations. Moreover, FEDs are heterogeneous, and there has been no examination of autistic traits in avoidant/restrictive food intake disorder (ARFID). METHODS: Therefore, we investigated the prevalence of ASD and autistic traits among Japanese children with AN (n = 92) or ARFID (n = 32) from a prospective multicenter cohort study using the Autism Spectrum Quotient Children's version (AQC) and Children's Eating Attitudes Test (ChEAT26). RESULTS: ASD prevalence was high in both AN and ARFID (16.3 and 12.5%, respectively). The AN group exhibited significantly higher scores on all AQC subscales than an age-matched healthy control (HC) group, but there were no significant correlations between AQC scores and ChEAT26 scores. In the AFRID group, AQC scores did not differ from HCs, but significant correlations were found between total AQC and ChEAT26 scores and between several AQC and ChEAT26 subscales. CONCLUSIONS: Both the AN and ARFID groups had high prevalence rates of ASD. The AN group showed a significantly higher degree of autistic traits than the HC group; however, no difference was found between the ARFID and HC groups. Clinicians need to be aware of these rates when working with children with ED.
BACKGROUND:Autism spectrum disorder (ASD) and feeding and eating disorders (FEDs) such as anorexia nervosa (AN) are strongly linked as evidenced by frequent comorbidity and overlapping traits. However, eating and social behaviors are shaped by culture, so it is critical to examine these associations in different populations. Moreover, FEDs are heterogeneous, and there has been no examination of autistic traits in avoidant/restrictive food intake disorder (ARFID). METHODS: Therefore, we investigated the prevalence of ASD and autistic traits among Japanese children with AN (n = 92) or ARFID (n = 32) from a prospective multicenter cohort study using the Autism Spectrum Quotient Children's version (AQC) and Children's Eating Attitudes Test (ChEAT26). RESULTS: ASD prevalence was high in both AN and ARFID (16.3 and 12.5%, respectively). The AN group exhibited significantly higher scores on all AQC subscales than an age-matched healthy control (HC) group, but there were no significant correlations between AQC scores and ChEAT26 scores. In the AFRID group, AQC scores did not differ from HCs, but significant correlations were found between total AQC and ChEAT26 scores and between several AQC and ChEAT26 subscales. CONCLUSIONS: Both the AN and ARFID groups had high prevalence rates of ASD. The AN group showed a significantly higher degree of autistic traits than the HC group; however, no difference was found between the ARFID and HC groups. Clinicians need to be aware of these rates when working with children with ED.
Entities:
Keywords:
Anorexia; Autism; Comorbidity; Feed and eating disorders
Authors: Martin M Fisher; David S Rosen; Rollyn M Ornstein; Kathleen A Mammel; Debra K Katzman; Ellen S Rome; S Todd Callahan; Joan Malizio; Sarah Kearney; B Timothy Walsh Journal: J Adolesc Health Date: 2014-02-05 Impact factor: 5.012
Authors: Johanna Louise Keeler; Janet Treasure; Mario F Juruena; Carol Kan; Hubertus Himmerich Journal: Nutrients Date: 2021-11-20 Impact factor: 5.717