Literature DB >> 33996179

Polymorphism of Proteasomal Genes Can Be a Risk Factor for Systemic Autoimmune Diseases in Children.

Ivan Y Bakutenko1, Irena D Hileuskaya1, Natalia V Nikitchenko1, Elena V Sechko2, Alexej M Tchitchko2, Galina M Batyan2, Alexander V Sukalo2, Nadezhda I Ryabokon1.   

Abstract

The study aimed to assess the involvement of three proteasomal genes, PSMA6 , PSMC6 , and PSMA3 , in autoimmune pathogenesis by analyzing associations between single nucleotide polymorphisms and systemic rheumatic diseases with a different autoimmune component: juvenile idiopathic arthritis (JIA), the juvenile form of systemic lupus erythematosus, and Kawasaki's disease (KD). Our results showed that the PSMA6 (rs1048990) polymorphism can be a risk factor for JIA (false discovery rate q ≤ 0.090), while PSMA3 (rs2348071) has a tendency to be nonspecific and is shared with JIA and other autoimmune diseases, including KD, an illness with very low autoimmune activity and high autoinflammation. Thieme. All rights reserved.

Entities:  

Keywords:  polymorphism; proteasomal gene; risk factor; systemic autoimmune diseases

Year:  2020        PMID： 33996179      PMCID： PMC8110351          DOI： 10.1055/s-0040-1714697

Source DB:  PubMed          Journal:  J Pediatr Genet        ISSN： 2146-460X


  29 in total

1.  International League of Associations for Rheumatology classification of juvenile idiopathic arthritis: second revision, Edmonton, 2001.

Authors:  Ross E Petty; Taunton R Southwood; Prudence Manners; John Baum; David N Glass; Jose Goldenberg; Xiaohu He; Jose Maldonado-Cocco; Javier Orozco-Alcala; Anne-Marie Prieur; Maria E Suarez-Almazor; Patricia Woo
Journal:  J Rheumatol       Date:  2004-02       Impact factor: 4.666

2.  SNPassoc: an R package to perform whole genome association studies.

Authors:  Juan R González; Lluís Armengol; Xavier Solé; Elisabet Guinó; Josep M Mercader; Xavier Estivill; Víctor Moreno
Journal:  Bioinformatics       Date:  2007-01-31       Impact factor: 6.937

3.  Kawasaki disease incidence in children and adolescents: an observational study in primary care.

Authors:  Gillian C Hall; Louise E Tulloh; Robert M R Tulloh
Journal:  Br J Gen Pract       Date:  2016-02-23       Impact factor: 5.386

4.  Understanding the addiction cycle: a complex biology with distinct contributions of genotype vs. sex at each stage.

Authors:  C J Wilhelm; J G Hashimoto; M L Roberts; M K Sonmez; K M Wiren
Journal:  Neuroscience       Date:  2014-09-04       Impact factor: 3.590

5.  Exosome-Transmitted PSMA3 and PSMA3-AS1 Promote Proteasome Inhibitor Resistance in Multiple Myeloma.

Authors:  Hongxia Xu; Huiying Han; Sha Song; Nengjun Yi; Chen'ao Qian; Yingchun Qiu; Wenqi Zhou; Yating Hong; Wenyue Zhuang; Zhengyi Li; Bingzong Li; Wenzhuo Zhuang
Journal:  Clin Cancer Res       Date:  2019-01-04       Impact factor: 12.531

6.  A functional SNP in PSMA6 confers risk of myocardial infarction in the Japanese population.

Authors:  Kouichi Ozaki; Hiroshi Sato; Aritoshi Iida; Hiroya Mizuno; Takahiro Nakamura; Yoshinari Miyamoto; Atsushi Takahashi; Tatsuhiko Tsunoda; Shiro Ikegawa; Naoyuki Kamatani; Masatsugu Hori; Yusuke Nakamura; Toshihiro Tanaka
Journal:  Nat Genet       Date:  2006-07-16       Impact factor: 38.330

Review 7.  Prevalence and incidence of juvenile idiopathic arthritis: a systematic review.

Authors:  Sigrid Thierry; Bruno Fautrel; Irène Lemelle; Francis Guillemin
Journal:  Joint Bone Spine       Date:  2013-11-06       Impact factor: 4.929

8.  A proposed classification of the immunological diseases.

Authors:  Dennis McGonagle; Michael F McDermott
Journal:  PLoS Med       Date:  2006-08       Impact factor: 11.069

9.  An integrated map of structural variation in 2,504 human genomes.

Authors:  Peter H Sudmant; Tobias Rausch; Eugene J Gardner; Robert E Handsaker; Alexej Abyzov; John Huddleston; Yan Zhang; Kai Ye; Goo Jun; Markus Hsi-Yang Fritz; Miriam K Konkel; Ankit Malhotra; Adrian M Stütz; Xinghua Shi; Francesco Paolo Casale; Jieming Chen; Fereydoun Hormozdiari; Gargi Dayama; Ken Chen; Maika Malig; Mark J P Chaisson; Klaudia Walter; Sascha Meiers; Seva Kashin; Erik Garrison; Adam Auton; Hugo Y K Lam; Xinmeng Jasmine Mu; Can Alkan; Danny Antaki; Taejeong Bae; Eliza Cerveira; Peter Chines; Zechen Chong; Laura Clarke; Elif Dal; Li Ding; Sarah Emery; Xian Fan; Madhusudan Gujral; Fatma Kahveci; Jeffrey M Kidd; Yu Kong; Eric-Wubbo Lameijer; Shane McCarthy; Paul Flicek; Richard A Gibbs; Gabor Marth; Christopher E Mason; Androniki Menelaou; Donna M Muzny; Bradley J Nelson; Amina Noor; Nicholas F Parrish; Matthew Pendleton; Andrew Quitadamo; Benjamin Raeder; Eric E Schadt; Mallory Romanovitch; Andreas Schlattl; Robert Sebra; Andrey A Shabalin; Andreas Untergasser; Jerilyn A Walker; Min Wang; Fuli Yu; Chengsheng Zhang; Jing Zhang; Xiangqun Zheng-Bradley; Wanding Zhou; Thomas Zichner; Jonathan Sebat; Mark A Batzer; Steven A McCarroll; Ryan E Mills; Mark B Gerstein; Ali Bashir; Oliver Stegle; Scott E Devine; Charles Lee; Evan E Eichler; Jan O Korbel
Journal:  Nature       Date:  2015-10-01       Impact factor: 49.962

10.  Long non-coding RNA PSMA3-AS1 promotes malignant phenotypes of esophageal cancer by modulating the miR-101/EZH2 axis as a ceRNA.

Authors:  Bai-Quan Qiu; Xia-Hui Lin; Xu-Dong Ye; Wei Huang; Xu Pei; Dian Xiong; Xiang Long; Shu-Qiang Zhu; Feng Lu; Kun Lin; Xiao-Qiang Zhang; Jian-Jun Xu; Lu-Lu Sheng; Xue-Mei Zhang; Peng-Fei Zhang; Yong-Bing Wu
Journal:  Aging (Albany NY)       Date:  2020-01-31       Impact factor: 5.682
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