Ufuk Utku Güllü1, Sevcan İpek2, Tahir Dalkıran3, Serpil Dinçer4, Sadık Yurttutan5, Eser Aynacı6. 1. Department of Pediatrics, Kahramanmaraş Sütçü İmam University Medical Faculty, Kahramanmaraş, Turkey; Department of Pediatric Cardiology, Kahramanmaraş Sütçü İmam University Medical Faculty, Kahramanmaraş, Turkey. 2. Department of Pediatrics, Kahramanmaraş Sütçü İmam University Medical Faculty, Kahramanmaraş, Turkey. Electronic address: drsevcanipek@gmail.com. 3. Pediatric Intensive Care Unit, Kahramanmaraş Necip Fazıl City Hospital, Kahramanmaraş, Turkey. 4. Department of Pediatrics, Kahramanmaraş Sütçü İmam University Medical Faculty, Kahramanmaraş, Turkey. 5. Department of Pediatrics, Kahramanmaraş Sütçü İmam University Medical Faculty, Kahramanmaraş, Turkey; Neonatal Intensive Care Unit, Kahramanmaraş Sütçü İmam University Medical Faculty, Kahramanmaraş, Turkey. 6. Department of Pediatrics, Kahramanmaraş Sütçü İmam University Medical Faculty, Kahramanmaraş, Turkey; Department of Pediatric Neurology, Kahramanmaraş Sütçü İmam University Medical Faculty, Kahramanmaraş, Turkey.
Abstract
INTRODUCTION: Scorpion stings are a major health problem with potentially fatal consequences. Children under the age of 10 y especially face a great risk. Predicting the prognosis is important in reducing mortality and morbidity because it enables the use of early treatment options. In this study, we examine the relationship between proBNP and prognosis in scorpion stings. METHODS: This is a retrospective analysis of patients aged ≤18 y who were admitted to the child emergency service with a scorpion sting. We examined the demographical data, clinical findings, laboratory records, treatments, and results of the patients. We classified stage 1 and stage 2 scorpion envenomation as group 1 (mild-moderate) and stage 3 and 4 as group 2 (severe). A t test was used for normally distributed data, and the Mann-Whitney U test was used for nonnormally distributed data. The correlation analysis was done using the Spearman test. RESULTS: There were 32 (74%) patients in the mild-moderate group and 11 (26%) in the severe group. ProBNP 1 was significantly higher in the severe group at admission (P=0.016). There was no difference between the troponin I values (P=0.051). ProBNP 2 (12th hour) and proBNP 3 (24th hour) were higher in the severe group (P=0.001 and P=0.032, respectively). There was a negative correlation between proBNP and echocardiographic findings involving ejection fraction and shortening fraction (R=-0.703, P=0.002). CONCLUSIONS: In our study, the first proBNP values were significantly higher in the severe group. This suggests that proBNP may be beneficial in predicting prognosis.
INTRODUCTION: Scorpion stings are a major health problem with potentially fatal consequences. Children under the age of 10 y especially face a great risk. Predicting the prognosis is important in reducing mortality and morbidity because it enables the use of early treatment options. In this study, we examine the relationship between proBNP and prognosis in scorpion stings. METHODS: This is a retrospective analysis of patients aged ≤18 y who were admitted to the child emergency service with a scorpion sting. We examined the demographical data, clinical findings, laboratory records, treatments, and results of the patients. We classified stage 1 and stage 2 scorpion envenomation as group 1 (mild-moderate) and stage 3 and 4 as group 2 (severe). A t test was used for normally distributed data, and the Mann-Whitney U test was used for nonnormally distributed data. The correlation analysis was done using the Spearman test. RESULTS: There were 32 (74%) patients in the mild-moderate group and 11 (26%) in the severe group. ProBNP 1 was significantly higher in the severe group at admission (P=0.016). There was no difference between the troponin I values (P=0.051). ProBNP 2 (12th hour) and proBNP 3 (24th hour) were higher in the severe group (P=0.001 and P=0.032, respectively). There was a negative correlation between proBNP and echocardiographic findings involving ejection fraction and shortening fraction (R=-0.703, P=0.002). CONCLUSIONS: In our study, the first proBNP values were significantly higher in the severe group. This suggests that proBNP may be beneficial in predicting prognosis.