Literature DB >> 339939

Analysis of heteroantisera to cells from human malignant effusions by immunofluorescence and protein A binding.

J P Birchall, J J Owen, B S Owen.   

Abstract

Using cultured cells derived from human malignant effusions, hetero-antisera were raised in rabbits. The antisera were sequentially absorbed on various human non-tumour cells, reactivity being monitored by immunofluorescence and 125I-labelled staphylococcal protein A assays. The absorbed antisera possessed common reactivity to all tumour cells assayed. This reactivity was not histogenically determined, and our data suggest that it was not directed to oncofoetal antigens.

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Year:  1977        PMID: 339939      PMCID: PMC2025566          DOI: 10.1038/bjc.1977.256

Source DB:  PubMed          Journal:  Br J Cancer        ISSN: 0007-0920            Impact factor:   7.640


  23 in total

Review 1.  PLATELET AND LEUKOCYTE ISOANTIGENS AND THEIR ANTIBODIES: SEROLOGIC PHYSIOLOGIC AND CLINICAL STUDIES.

Authors:  N R SHULMAN; V J MARDER; M C HILLER; E M COLLIER
Journal:  Prog Hematol       Date:  1964

2.  A cell-surface antigen common to human tumours: detection, localization and characterization.

Authors:  J P Dickinson; J J Smith; J E Dyson
Journal:  Biochem Soc Trans       Date:  1976       Impact factor: 5.407

3.  Clonal variation and interaction of cells with viruses.

Authors:  W H MURPHY; B J LANDAU
Journal:  Natl Cancer Inst Monogr       Date:  1962-04

4.  Immune responses induced by human malignant melanoma in the rabbit.

Authors:  D P Goodwin; M O Hornung; S P Leong; E T Krementz
Journal:  Surgery       Date:  1972-11       Impact factor: 3.982

5.  Production of tumor-specific antibody in the xenogeneic host: use of blocking antibody.

Authors:  R S Weiner; J D Hubbard; M R Mardiney
Journal:  J Natl Cancer Inst       Date:  1972-10       Impact factor: 13.506

6.  Immunofluorescence studies of benign and malignant human mammary tissue.

Authors:  A V Richman
Journal:  J Natl Cancer Inst       Date:  1976-08       Impact factor: 13.506

7.  Human leukemia cell antigens: serologic characterization with xenoantisera.

Authors:  T Mohanakumar; R S Metzgar; D S Miller
Journal:  J Natl Cancer Inst       Date:  1974-05       Impact factor: 13.506

8.  Membrane associated antigens of human malignant melanoma. III. Specificity of human sera reacting with cultured melanoma cells.

Authors:  E Seibert; C Sorg; R Happle; E Macher
Journal:  Int J Cancer       Date:  1977-02-15       Impact factor: 7.396

9.  A membrane antigen common to human cancer and fetal brain tissues.

Authors:  R F Irie; K Irie; D L Morton
Journal:  Cancer Res       Date:  1976-09       Impact factor: 12.701

10.  Cell surface antigens of human malignant melanoma. II. Serological typing with immune adherence assays and definition of two new surface antigens.

Authors:  H Shiku; T Takahashi; H F Oettgen
Journal:  J Exp Med       Date:  1976-10-01       Impact factor: 14.307

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