Literature DB >> 33993722

Pharmacological and Genetic Blockade of Trpm7 in the Carotid Body Treats Obesity-Induced Hypertension.

Mi-Kyung Shin1, Roxana Mitrut2, Chenjuan Gu1, Lenise J Kim1, Bonnie H Y Yeung3, Rachel Lee1, Luu Pham1, Wan-Yee Tang4, James S K Sham1, Honggang Cui2, Vsevolod Y Polotsky1.   

Abstract

[Figure: see text].

Entities:  

Keywords:  blood pressure; carotid body; femoral artery; hydrogels; leptin

Mesh：

Substances：

Year:  2021        PMID： 33993722      PMCID： PMC8192446          DOI： 10.1161/HYPERTENSIONAHA.120.16527

Source DB:  PubMed          Journal:  Hypertension        ISSN： 0194-911X            Impact factor:   9.897


  58 in total

1.  High fat diet blunts the effects of leptin on ventilation and on carotid body activity.

Authors:  Maria J Ribeiro; Joana F Sacramento; Teresa Gallego-Martin; Elena Olea; Bernardete F Melo; Maria P Guarino; Sara Yubero; Ana Obeso; Silvia V Conde
Journal:  J Physiol       Date:  2018-01-15       Impact factor: 5.182

2.  Natural and synthetic modulators of SK (K(ca)2) potassium channels inhibit magnesium-dependent activity of the kinase-coupled cation channel TRPM7.

Authors:  V Chubanov; M Mederos y Schnitzler; M Meißner; S Schäfer; K Abstiens; T Hofmann; T Gudermann
Journal:  Br J Pharmacol       Date:  2012-06       Impact factor: 8.739

3.  Prevalence of Apparent Treatment-Resistant Hypertension in the United States.

Authors:  Robert M Carey; Swati Sakhuja; David A Calhoun; Paul K Whelton; Paul Muntner
Journal:  Hypertension       Date:  2019-02       Impact factor: 10.190

Review 4.  Signal processing at mammalian carotid body chemoreceptors.

Authors:  Colin A Nurse; Nikol A Piskuric
Journal:  Semin Cell Dev Biol       Date:  2012-09-26       Impact factor: 7.727

5.  Hypertension in overweight and obese primary care patients is highly prevalent and poorly controlled.

Authors:  Peter Bramlage; David Pittrow; Hans-Ulrich Wittchen; Wilhelm Kirch; Steffen Boehler; Hendrik Lehnert; Michael Hoefler; Thomas Unger; Arya M Sharma
Journal:  Am J Hypertens       Date:  2004-10       Impact factor: 2.689

6.  Leptin Induces Hypertension Acting on Transient Receptor Potential Melastatin 7 Channel in the Carotid Body.

Authors:  Mi-Kyung Shin; Candela Caballero Eraso; Yun-Ping Mu; Chenjuan Gu; Bonnie H Y Yeung; Lenise J Kim; Xiao-Ru Liu; Zhi-Juan Wu; Omkar Paudel; Luis E Pichard; Machiko Shirahata; Wan-Yee Tang; James S K Sham; Vsevolod Y Polotsky
Journal:  Circ Res       Date:  2019-09-23       Impact factor: 17.367

Review 7.  Leptin receptor signaling: pathways to leptin resistance.

Authors:  Joris Wauman; Jan Tavernier
Journal:  Front Biosci (Landmark Ed)       Date:  2011-06-01

8.  Identification and expression cloning of a leptin receptor, OB-R.

Authors:  L A Tartaglia; M Dembski; X Weng; N Deng; J Culpepper; R Devos; G J Richards; L A Campfield; F T Clark; J Deeds; C Muir; S Sanker; A Moriarty; K J Moore; J S Smutko; G G Mays; E A Wool; C A Monroe; R I Tepper
Journal:  Cell       Date:  1995-12-29       Impact factor: 41.582

9.  Carotid body denervation prevents the development of insulin resistance and hypertension induced by hypercaloric diets.

Authors:  Maria J Ribeiro; Joana F Sacramento; Constancio Gonzalez; Maria P Guarino; Emília C Monteiro; Sílvia V Conde
Journal:  Diabetes       Date:  2013-03-25       Impact factor: 9.461

Review 10.  Carotid Body and Metabolic Syndrome: Mechanisms and Potential Therapeutic Targets.

Authors:  Lenise J Kim; Vsevolod Y Polotsky
Journal:  Int J Mol Sci       Date:  2020-07-20       Impact factor: 5.923
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  2 in total

Review 1.  Are Multiple Mitochondrial Related Signalling Pathways Involved in Carotid Body Oxygen Sensing?

Authors:  Andrew P Holmes; Agnieszka Swiderska; Demitris Nathanael; Hayyaf S Aldossary; Clare J Ray; Andrew M Coney; Prem Kumar
Journal:  Front Physiol       Date:  2022-05-31       Impact factor: 4.755

2.  Leptin Receptor Blockade Attenuates Hypertension, but Does Not Affect Ventilatory Response to Hypoxia in a Model of Polygenic Obesity.

Authors:  Lenise J Kim; Mi-Kyung Shin; Huy Pho; Laszlo Otvos; Sergio Tufik; Monica L Andersen; Luu V Pham; Vsevolod Y Polotsky
Journal:  Front Physiol       Date:  2021-07-02       Impact factor: 4.566
  2 in total

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