Literature DB >> 33993228

BNT162b2 Messenger RNA Vaccination Did Not Prevent an Outbreak of Severe Acute Respiratory Syndrome Coronavirus 2 Variant 501Y.V2 in an Elderly Nursing Home but Reduced Transmission and Disease Severity.

Benoit Bailly1,2, Luc Guilpain3, Kevin Bouiller2,4, Catherine Chirouze2,4, Melissa N'Debi5, Alexandre Soulier6, Vanessa Demontant5, Jean-Michel Pawlotsky6,7, Christophe Rodriguez5,6,7, Slim Fourati6,7.   

Abstract

We report an outbreak of severe acute respiratory syndrome coronavirus 2 501Y.V2 in a nursing home. All nonvaccinated residents (5/5) versus half of those vaccinated with BNT162b2 (13/26) were infected. Two of 13 vaccinated versus 4 of 5 nonvaccinated residents presented severe disease. BNT162b2 did not prevent the outbreak, but reduced transmission and disease severity.
© The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  BNT162b2 vaccine; SARS CoV-2; nursing home; outbreak; variant

Mesh：

Substances：

Year:  2022        PMID： 33993228      PMCID： PMC8241482          DOI： 10.1093/cid/ciab446

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   9.079


  11 in total

1.  Real-Word Effectiveness of Global COVID-19 Vaccines Against SARS-CoV-2 Variants: A Systematic Review and Meta-Analysis.

Authors:  Kai Wang; Lin Wang; Mingzhe Li; Bing Xie; Lu He; Meiyu Wang; Rumin Zhang; Nianzong Hou; Yi Zhang; Fusen Jia
Journal:  Front Med (Lausanne)       Date:  2022-05-19

Review 2.  SARS-CoV-2 Portrayed against HIV: Contrary Viral Strategies in Similar Disguise.

Authors:  Ralf Duerr; Keaton M Crosse; Ana M Valero-Jimenez; Meike Dittmann
Journal:  Microorganisms       Date:  2021-06-27

3.  Rapid antigen testing as a reactive response to surges in nosocomial SARS-CoV-2 outbreak risk.

Authors:  David R M Smith; Audrey Duval; Jean Ralph Zahar; Lulla Opatowski; Laura Temime
Journal:  Nat Commun       Date:  2022-01-11       Impact factor: 14.919

4.  Receptor binding domain-IgG levels correlate with protection in residents facing SARS-CoV-2 B.1.1.7 outbreaks.

Authors:  Hubert Blain; Edouard Tuaillon; Lucie Gamon; Amandine Pisoni; Stéphanie Miot; Valentin Delpui; Nejm Si-Mohamed; Clémence Niel; Yves Rolland; Brigitte Montes; Soraya Groc; Sophia Rafasse; Anne-Marie Dupuy; Nathalie Gros; Delphine Muriaux; Marie-Christine Picot; Jean Bousquet
Journal:  Allergy       Date:  2021-10-29       Impact factor: 14.710

5.  Impaired immunity and high attack rates caused by SARS-CoV-2 variants among vaccinated long-term care facility residents.

Authors:  Dorothée Obach; Anna Solastie; Oona Liedes; Saimi Vara; Eva Krzyżewska-Dudek; Luise Brinkmann; Anu Haveri; Charlotte C Hammer; Timothée Dub; Seppo Meri; Tobias L Freitag; Outi Lyytikäinen; Merit Melin
Journal:  Immun Inflamm Dis       Date:  2022-09

6.  A SARS-CoV-2 Negative Antigen Rapid Diagnostic in RT-qPCR Positive Samples Correlates With a Low Likelihood of Infectious Viruses in the Nasopharynx.

Authors:  Isadora Alonso Corrêa; Débora Souza Faffe; Rafael Mello Galliez; Cássia Cristina Alves Gonçalves; Richard Araújo Maia; Gustavo Peixoto da Silva; Filipe Romero Rebello Moreira; Diana Mariani; Mariana Freire Campos; Isabela de Carvalho Leitão; Marcos Romário de Souza; Marcela Sabino Cunha; Érica Ramos Dos Santos Nascimento; Liane de Jesus Ribeiro; Thais Felix Cordeiro da Cruz; Cintia Policarpo; Luis Gonzales; Mary A Rodgers; Michael Berg; Roy Vijesurier; Gavin A Cloherty; John Hackett; Orlando da Costa Ferreira; Terezinha Marta Pereira Pinto Castiñeiras; Amilcar Tanuri; Luciana Jesus da Costa
Journal:  Front Microbiol       Date:  2022-07-27       Impact factor: 6.064

7.  Does potential antibody-dependent enhancement occur during SARS-CoV-2 infection after natural infection or vaccination? A meta-analysis.

Authors:  Lin Gan; Yan Chen; Jinlin Tan; Xuezhi Wang; Dingmei Zhang
Journal:  BMC Infect Dis       Date:  2022-09-19       Impact factor: 3.667

Review 8.  Nature of Acquired Immune Responses, Epitope Specificity and Resultant Protection from SARS-CoV-2.

Authors:  Reginald M Gorczynski; Robyn A Lindley; Edward J Steele; Nalin Chandra Wickramasinghe
Journal:  J Pers Med       Date:  2021-11-25

9.  Disentangling post-vaccination symptoms from early COVID-19.

Authors:  Liane S Canas; Marc F Österdahl; Jie Deng; Christina Hu; Somesh Selvachandran; Lorenzo Polidori; Anna May; Erika Molteni; Benjamin Murray; Liyuan Chen; Eric Kerfoot; Kerstin Klaser; Michela Antonelli; Alexander Hammers; Tim Spector; Sebastien Ourselin; Claire Steves; Carole H Sudre; Marc Modat; Emma L Duncan
Journal:  EClinicalMedicine       Date:  2021-12-01

10.  Breakthrough Infections of SARS-CoV-2 Gamma Variant in Fully Vaccinated Gold Miners, French Guiana, 2021.

Authors:  Nicolas Vignier; Vincent Bérot; Nathalie Bonnave; Sandrine Peugny; Mathilde Ballet; Estelle Jacoud; Céline Michaud; Mélanie Gaillet; Félix Djossou; Denis Blanchet; Anne Lavergne; Magalie Demar; Mathieu Nacher; Dominique Rousset; Loïc Epelboin
Journal:  Emerg Infect Dis       Date:  2021-07-21       Impact factor: 6.883
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