Literature DB >> 33988797

Pharmacological and therapeutic applications of Sinapic acid-an updated review.

Anandakumar Pandi1, Vanitha Manickam Kalappan2.   

Abstract

Phenolic compounds, present in plants, are considered to be indispensable parts of human dietary sources. Sinapic acid, is a natural herbal compound containing phenolic acid. It is found in oranges, grapefruits, and cranberries and in herbs like canola, mustard seed and rapeseed. Sinapic acid is chemically studied as a cinnamic acid derivative that contains 3, 5-dimethoxyl and 4-hydroxyl substitutions in the phenyl group of cinnamic acid. Sinapic acid has been pharmacologically evaluated for its potent antioxidant, anti-inflammatory, anti-cancer, hepatoprotective, cardioprotective, renoprotective, neuroprotective, anti-diabetic, anxiolytic and anti-bacterial activities. In this review we have summarized the potential pharmacological and therapeutic effects of Sinapic acid in various models.

Entities:  

Keywords:  Anti-cancer; Anti-inflammatory; Antioxidant; Cardioprotective; Neuroprotective; Sinapic acid

Year:  2021        PMID： 33988797     DOI： 10.1007/s11033-021-06367-0

Source DB:  PubMed          Journal:  Mol Biol Rep        ISSN： 0301-4851            Impact factor:   2.316


  48 in total

1.  Metabolism of Sinapine in Mustard Plants. II. Purification & Some Properties of Sinapine Esterase.

Authors:  A Tzagoloff
Journal:  Plant Physiol       Date:  1963-03       Impact factor: 8.340

2.  Sinapic Acid and Its Derivatives: Natural Sources and Bioactivity.

Authors:  Neda Nićiforović; Helena Abramovič
Journal:  Compr Rev Food Sci Food Saf       Date:  2014-01       Impact factor: 12.811

3.  Isolation of sinapic acid from broccoli using molecularly imprinted polymers.

Authors:  Heba Hosny; Nesrine El Gohary; Engy Saad; Heba Handoussa; Rasha M El Nashar
Journal:  J Sep Sci       Date:  2018-01-12       Impact factor: 3.645

4.  Synthesis and antioxidant activity of long chain alkyl hydroxycinnamates.

Authors:  Jose C J M D S Menezes; Shrivallabh P Kamat; Jose A S Cavaleiro; Alexandra Gaspar; Jorge Garrido; Fernanda Borges
Journal:  Eur J Med Chem       Date:  2010-12-21       Impact factor: 6.514

5.  Phenolics as potential antioxidant therapeutic agents: mechanism and actions.

Authors:  M A Soobrattee; V S Neergheen; A Luximon-Ramma; O I Aruoma; T Bahorun
Journal:  Mutat Res       Date:  2005-08-26       Impact factor: 2.433

6.  Absorption of hydroxycinnamates in humans after high-bran cereal consumption.

Authors:  Sandra M Kern; Richard N Bennett; Fred A Mellon; Paul Anthony Kroon; Maria-Teresa Garcia-Conesa
Journal:  J Agric Food Chem       Date:  2003-09-24       Impact factor: 5.279

7.  Separation, characterization, and quantitation of benzoic and phenolic antioxidants in American cranberry fruit by GC-MS.

Authors:  Yuegang Zuo; Chengxia Wang; Jian Zhan
Journal:  J Agric Food Chem       Date:  2002-06-19       Impact factor: 5.279

Review 8.  Occurrence and content of hydroxycinnamic and hydroxybenzoic acid compounds in foods.

Authors:  K Herrmann
Journal:  Crit Rev Food Sci Nutr       Date:  1989       Impact factor: 11.176

Review 9.  The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety.

Authors:  Martins Ekor
Journal:  Front Pharmacol       Date:  2014-01-10       Impact factor: 5.810

Review 10.  Sinapic Acid and Its Derivatives as Medicine in Oxidative Stress-Induced Diseases and Aging.

Authors:  Chunye Chen
Journal:  Oxid Med Cell Longev       Date:  2015-11-10       Impact factor: 6.543
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  6 in total

1.  Modulation of immunological responses by aqueous extract of Datura stramonium L. seeds on cyclophosphamide-induced immunosuppression in Wistar rats.

Authors:  Parker Elijah Joshua; Junaidu Yahaya; Daniel Emmanuel Ekpo; Joyce Oloaigbe Ogidigo; Arome Solomon Odiba; Rita Onyekachukwu Asomadu; Samson Ayodeji Oka; Olasupo Stephen Adeniyi
Journal:  BMC Immunol       Date:  2022-10-19       Impact factor: 3.594

2.  Flaxseed Ethanol Extract Effect in Acute Experimental Inflammation.

Authors:  Elisabeta Ioana Chera; Tiberia Ioana Pop; Raluca Maria Pop; Marcel Pârvu; Ana Uifălean; Florinela Adriana Cătoi; Andra Diana Cecan; Camelia Manuela Mîrza; Patriciu Achimaș-Cadariu; Alina Elena Pârvu
Journal:  Medicina (Kaunas)       Date:  2022-04-24       Impact factor: 2.948

3.  Flaxseed Ethanol Extracts' Antitumor, Antioxidant, and Anti-Inflammatory Potential.

Authors:  Elisabeta Ioana Chera; Raluca Maria Pop; Marcel Pârvu; Olga Sorițău; Ana Uifălean; Florinela Adriana Cătoi; Andra Cecan; Andrada Gabriela Negoescu; Patriciu Achimaș-Cadariu; Alina Elena Pârvu
Journal:  Antioxidants (Basel)       Date:  2022-04-30

4.  Sinapic acid attenuates muscle atrophy in streptozotocin-induced diabetic mice.

Authors:  Liu Xianchu; Liu Ming; Cheng Changhao; Deng Beiwang; Xie Jingtao
Journal:  Iran J Basic Med Sci       Date:  2021-12       Impact factor: 2.699

5.  Changes in the Polyphenolic Profile and Antioxidant Activity of Wheat Bread after Incorporating Quinoa Flour.

Authors:  José Vicente Gil; Adelaida Esteban-Muñoz; María Teresa Fernández-Espinar
Journal:  Antioxidants (Basel)       Date:  2021-12-24

6.  Study of Biological Activities and ADMET-Related Properties of Novel Chlorinated N-arylcinnamamides.

Authors:  Tomas Strharsky; Dominika Pindjakova; Jiri Kos; Lucia Vrablova; Hana Michnova; Jan Hosek; Nicol Strakova; Veronika Lelakova; Lenka Leva; Lenka Kavanova; Michal Oravec; Alois Cizek; Josef Jampilek
Journal:  Int J Mol Sci       Date:  2022-03-15       Impact factor: 5.923
  6 in total

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