| Literature DB >> 3398705 |
Y Makino1, S Ohta, O Tachikawa, M Hirobe.
Abstract
This is the first report confirming the presence of 1,2,3,4-tetrahydroisoquinoline (TIQ) and 1-methyl-1,2,3,4-tetrahydroisoquinoline(1MeTIQ) in a number of foods with a high 2-phenylethylamine content. These compounds were determined by gas chromatography-mass spectrometry. This study also confirmed that 1MeTIQ and TIQ can cross the blood-brain barrier in rat. Thus, these compounds, suspected to have relation to parkinson's disease, may accumulate in the brain from food sources.Entities:
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Year: 1988 PMID： 3398705 DOI： 10.1016/0024-3205(88)90115-4
Source DB: PubMed Journal: Life Sci ISSN： 0024-3205 Impact factor: 5.037