Literature DB >> 33986570

Prevalence of and Characteristics Associated With Overbasalization Among Patients With Type 2 Diabetes Using Basal Insulin: A Cross-Sectional Study.

Kevin Cowart1,2, Wendy H Updike1,3, Rashmi Pathak4.   

Abstract

This article describes a cross-sectional analysis of 655 patients to determine the prevalence of and patient-specific characteristics associated with overbasalization in patients with type 2 diabetes. Overbasalization was defined as uncontrolled A1C (>8%) plus a basal insulin dose >0.5 units/kg/day. The period prevalence of overbasalization was found to be 38.1, 42.7, and 42% for those with an A1C >8, ≥9, and ≥10%, respectively. Those with an A1C ≥9% had the greatest likelihood of experiencing overbasalization. These results suggest that overbasalization may play a role in patients not achieving optimal glycemic control in type 2 diabetes.
© 2021 by the American Diabetes Association.

Entities:  

Year:  2021        PMID: 33986570      PMCID: PMC8061546          DOI: 10.2337/cd20-0080

Source DB:  PubMed          Journal:  Clin Diabetes        ISSN: 0891-8929


  8 in total

1.  Insulin for type 2 diabetes: How and when to get started.

Authors:  Jay H Shubrook
Journal:  J Fam Pract       Date:  2014-02       Impact factor: 0.493

2.  CONSENSUS STATEMENT BY THE AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY ON THE COMPREHENSIVE TYPE 2 DIABETES MANAGEMENT ALGORITHM - 2020 EXECUTIVE SUMMARY.

Authors:  Alan J Garber; Yehuda Handelsman; George Grunberger; Daniel Einhorn; Martin J Abrahamson; Joshua I Barzilay; Lawrence Blonde; Michael A Bush; Ralph A DeFronzo; Jeffrey R Garber; W Timothy Garvey; Irl B Hirsch; Paul S Jellinger; Janet B McGill; Jeffrey I Mechanick; Leigh Perreault; Paul D Rosenblit; Susan Samson; Guillermo E Umpierrez
Journal:  Endocr Pract       Date:  2020-01       Impact factor: 3.443

Review 3.  Overbasalization: Addressing Hesitancy in Treatment Intensification Beyond Basal Insulin.

Authors:  Kevin Cowart
Journal:  Clin Diabetes       Date:  2020-07

Review 4.  Insulin therapy in type 2 diabetes mellitus: a practical approach for primary care physicians and other health care professionals.

Authors:  James R LaSalle; Rachele Berria
Journal:  J Am Osteopath Assoc       Date:  2013-02

Review 5.  Anticipatory guidance in type 2 diabetes to improve disease management; next steps after basal insulin.

Authors:  Eric L Johnson; Juan P Frias; Jennifer M Trujillo
Journal:  Postgrad Med       Date:  2018-03-23       Impact factor: 3.840

Review 6.  9. Pharmacologic Approaches to Glycemic Treatment: Standards of Medical Care in Diabetes-2020.

Authors: 
Journal:  Diabetes Care       Date:  2020-01       Impact factor: 19.112

7.  When basal insulin is not enough: A dose-response relationship between insulin glargine 100 units/mL and glycaemic control.

Authors:  Guillermo E Umpierrez; Neil Skolnik; Terry Dex; Louise Traylor; Jason Chao; Charles Shaefer
Journal:  Diabetes Obes Metab       Date:  2019-03-25       Impact factor: 6.577

Review 8.  Appropriate Titration of Basal Insulin in Type 2 Diabetes and the Potential Role of the Pharmacist.

Authors:  Dhiren Patel; Curtis Triplitt; Jennifer Trujillo
Journal:  Adv Ther       Date:  2019-03-21       Impact factor: 3.845

  8 in total
  2 in total

1.  Practicable Measurement and Identification of Overbasalization.

Authors:  Kevin Cowart; Nicholas W Carris
Journal:  Clin Diabetes       Date:  2022-01

2.  The Clinical Definition of Overbasalization.

Authors:  Mayer B Davidson
Journal:  Clin Diabetes       Date:  2021-10
  2 in total

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