Arpitha Chiruvolu1,2, Kevin M Claunch3, Alberto J Garcia4, Barbara Petrey5, Kendall Hammonds6, Lea H Mallett7. 1. Department of Women and Infants, Baylor Scott & White Medical Center, McKinney, TX, USA. Arpitha.Chiruvolu@bswhealth.org. 2. Pediatrix Medical Group of Dallas, Dallas, TX, USA. Arpitha.Chiruvolu@bswhealth.org. 3. Department of Pediatrics, Naval Medical Center, Portsmouth, VA, USA. 4. Department of Cardiopulmonary, Baylor Scott & White Medical Center, McKinney, TX, USA. 5. Department of Women and Infants, Baylor Scott & White Medical Center, McKinney, TX, USA. 6. Department of Biostatistics, Baylor Scott & White McLane Children's Medical Center, Temple, TX, USA. 7. Department of Pediatrics, Baylor Scott & White McLane Children's Medical Center, Temple, TX, USA.
Abstract
OBJECTIVE: To compare continuous positive airway pressure (CPAP) with nasal cannula (NC) as primary noninvasive respiratory therapy in hypoxic infants for transient tachypnea of the newborn (TTN). STUDY DESIGN: Retrospective cohort study of infants born at ≥34 weeks of gestation between January 1, 2015 and December 31, 2018. RESULT: After adjusting for gestational age and birth weight, the maximum fractional inspired oxygen (FiO2) was significantly lower in the CPAP group with an incidence rate ratio (IRR) of 0.85 (95% CI: 0.76-0.96). Although nonsignificant, the CPAP group needed 32% fewer hours on oxygen with an IRR of 0.68 (95% CI: 0.38-1.22). The duration of respiratory support and the incidence of pneumothorax were similar between both groups. CONCLUSION: Comparing CPAP with NC as initial noninvasive respiratory therapy for TTN, significantly lower maximum FiO2 was observed in the infants of CPAP group without increase in the incidence of pneumothorax.
OBJECTIVE: To compare continuous positive airway pressure (CPAP) with nasal cannula (NC) as primary noninvasive respiratory therapy in hypoxic infants for transient tachypnea of the newborn (TTN). STUDY DESIGN: Retrospective cohort study of infants born at ≥34 weeks of gestation between January 1, 2015 and December 31, 2018. RESULT: After adjusting for gestational age and birth weight, the maximum fractional inspired oxygen (FiO2) was significantly lower in the CPAP group with an incidence rate ratio (IRR) of 0.85 (95% CI: 0.76-0.96). Although nonsignificant, the CPAP group needed 32% fewer hours on oxygen with an IRR of 0.68 (95% CI: 0.38-1.22). The duration of respiratory support and the incidence of pneumothorax were similar between both groups. CONCLUSION: Comparing CPAP with NC as initial noninvasive respiratory therapy for TTN, significantly lower maximum FiO2 was observed in the infants of CPAP group without increase in the incidence of pneumothorax.
Authors: Erin V McGillick; Arjan B Te Pas; Thomas van den Akker; J M H Keus; Marta Thio; Stuart B Hooper Journal: Front Pediatr Date: 2022-06-23 Impact factor: 3.569