| Literature DB >> 33984739 |
Pamela Raquel Rivera-Tovar1, María Dolores Torres2, Conrado Camilo3, María Salomé Mariotti-Celis4, Herminia Domínguez2, José Ricardo Pérez-Correa5.
Abstract
Multi-response optimization of hot pressurized liquid extraction (HPLE) was applied for the first time to obtain maqui (Aristotelia chilensis [Mol.] Stuntz) leaf extracts. The total polyphenol content (TPC), the antioxidant capacity (AC) as well as the total polyphenol purity of the maqui leaf extracts were accurately predicted (RSD < 8%) at the evaluated extraction scales. The optimum HPLE conditions that prioritized TPC and AC equally (OPT1) recovered ~3 times more TPC (205.14 mg GAE/g leaves) than maqui leaf extracts obtained by maceration, while the extract that prioritized purity over TPC and AC presented the highest purity (36.29%) and an EC50 ~3 times lower than currently reported values. It was found by multi-response optimization that maqui leaves and HPLE are among the best natural sources and extraction techniques, respectively, to recover protocatechuic acid, quercetin, and catechin.Entities:
Keywords: Accelerated solvent extraction (ASE); Chlorogenic acid (PubChem CID1794427); Desirability function (DF); Extract’s polyphenol purity; Gallic acid (PubChem CID370); Number of cycles; Polyphenol extraction yield; Response surface methodology (RSM); catechin (PubChem CID9064); cinnamic acid (PubChem CID444539); coumaric acid (PubChem CID637542); hydroxytyrosol (PubChem CID82755); kaempferol (PubChem CID5280863); protocatechuic acid (PubChem CID72); quercetin (PubChem CID5280343); resveratrol (PubChem CID445154)
Year: 2021 PMID: 33984739 DOI: 10.1016/j.foodchem.2021.129729
Source DB: PubMed Journal: Food Chem ISSN: 0308-8146 Impact factor: 7.514