| Literature DB >> 33983594 |
Eun-Shin Lee1, Jongjin Kim2, Wonshik Han3.
Abstract
As sequencing technology and information of the genomic causes for cancer development expand, multi-gene panel testing for hereditary cancer is increasing in clinical practice. In this chapter, we reviewed the application of multi-gene panel with pre-/post- testing considerations and summarized genetic counseling based on panel testing results in clinical field. In addition, we introduce multi-gene panel for hereditary cancer developed in Seoul National University Hospital.Entities:
Keywords: BRCA1/2 gene mutation; Breast cancer susceptibility; Genetic counseling; Hereditary/familial breast cancer; High penetrance gene; Multigene panel testing; Next-generation sequencing
Mesh：
Year: 2021 PMID： 33983594 DOI： 10.1007/978-981-32-9620-6_24
Source DB: PubMed Journal: Adv Exp Med Biol ISSN： 0065-2598 Impact factor: 2.622