| Literature DB >> 33982577 |
P Borsky1, Z Fiala, C Andrys, M Beranek, K Hamakova, J Kremlacek, A Malkova, T Svadlakova, J Krejsek, V Palicka, V Rehacek, L Kotingova, L Borska.
Abstract
The study aimed to contribute to understanding the role of CRP, chemerin, fetuin-A and osteopontin and to assess their suitability as biomarkers of early stages of cardiovascular diseases in psoriasis vulgaris. Serum levels measured in 28 patients and 22 controls. Patients: increased levels of CRP (p<0.001), chemerin (p<0.05), osteopontin (p<0.05) and decreased levels of fetuin-A (p<0.05), significant relationships between CRP and fetuin-A (rho=0.530, p<0.01), CRP and chemerin (rho=0.543, p<0.01), CRP and age (rho=0.590, p<0.001), osteopontin and fetuin-A (r=-0.415, p<0.05), chemerin and PASI score (rho=-0.424, p<0.05). We confirmed specific roles of the biomarkers in psoriasis. CRP, fetuin-A and osteopontin could be considered appropriate markers for the detection of early stages of cardiovascular diseases.Entities:
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Year: 2021 PMID： 33982577 PMCID： PMC8820567 DOI： 10.33549/physiolres.934654
Source DB: PubMed Journal: Physiol Res ISSN： 0862-8408 Impact factor: 1.881