Literature DB >> 33979874

Infobuttons for Genomic Medicine: Requirements and Barriers.

Luke V Rasmussen1, John J Connolly2, Guilherme Del Fiol3, Robert R Freimuth4, Douglas B Pet5, Josh F Peterson6, Brian H Shirts7, Justin B Starren1, Marc S Williams8, Nephi Walton8,9, Casey Overby Taylor8,10.   

Abstract

OBJECTIVES: The study aimed to understand potential barriers to the adoption of health information technology projects that are released as free and open source software (FOSS).
METHODS: We conducted a survey of research consortia participants engaged in genomic medicine implementation to assess perceived institutional barriers to the adoption of three systems: ClinGen electronic health record (EHR) Toolkit, DocUBuild, and MyResults.org. The survey included eight barriers from the Consolidated Framework for Implementation Research (CFIR), with additional barriers identified from a qualitative analysis of open-ended responses.
RESULTS: We analyzed responses from 24 research consortia participants from 18 institutions. In total, 14 categories of perceived barriers were evaluated, which were consistent with other observed barriers to FOSS adoption. The most frequent perceived barriers included lack of adaptability of the system, lack of institutional priority to implement, lack of trialability, lack of advantage of alternative systems, and complexity.
CONCLUSION: In addition to understanding potential barriers, we recommend some strategies to address them (where possible), including considerations for genomic medicine. Overall, FOSS developers need to ensure systems are easy to trial and implement and need to clearly articulate benefits of their systems, especially when alternatives exist. Institutional champions will remain a critical component to prioritizing genomic medicine projects. Thieme. All rights reserved.

Entities:  

Mesh:

Year:  2021        PMID: 33979874      PMCID: PMC8116174          DOI: 10.1055/s-0041-1729164

Source DB:  PubMed          Journal:  Appl Clin Inform        ISSN: 1869-0327            Impact factor:   2.342


  17 in total

1.  Supporting infobuttons with terminological knowledge.

Authors:  J J Cimino; G Elhanan; Q Zeng
Journal:  Proc AMIA Annu Fall Symp       Date:  1997

Review 2.  OPEN-SOURCE SOFTWARE IN DENTISTRY: A SYSTEMATIC REVIEW.

Authors:  Małgorzata Chruściel-Nogalska; Tomasz Smektała; Marcin Tutak; Katarzyna Sporniak-Tutak; Raphael Olszewski
Journal:  Int J Technol Assess Health Care       Date:  2017-08-31       Impact factor: 2.188

3.  ClinGen--the Clinical Genome Resource.

Authors:  Heidi L Rehm; Jonathan S Berg; Lisa D Brooks; Carlos D Bustamante; James P Evans; Melissa J Landrum; David H Ledbetter; Donna R Maglott; Christa Lese Martin; Robert L Nussbaum; Sharon E Plon; Erin M Ramos; Stephen T Sherry; Michael S Watson
Journal:  N Engl J Med       Date:  2015-05-27       Impact factor: 91.245

4.  Use of more than one electronic medical record system within a single health care organization.

Authors:  T Payne; J Fellner; C Dugowson; D Liebovitz; G Fletcher
Journal:  Appl Clin Inform       Date:  2012-12-12       Impact factor: 2.342

5.  Ten key considerations for the successful implementation and adoption of large-scale health information technology.

Authors:  Kathrin M Cresswell; David W Bates; Aziz Sheikh
Journal:  J Am Med Inform Assoc       Date:  2013-04-18       Impact factor: 4.497

6.  SMART on FHIR: a standards-based, interoperable apps platform for electronic health records.

Authors:  Joshua C Mandel; David A Kreda; Kenneth D Mandl; Isaac S Kohane; Rachel B Ramoni
Journal:  J Am Med Inform Assoc       Date:  2016-02-17       Impact factor: 4.497

7.  ClinVar: improving access to variant interpretations and supporting evidence.

Authors:  Melissa J Landrum; Jennifer M Lee; Mark Benson; Garth R Brown; Chen Chao; Shanmuga Chitipiralla; Baoshan Gu; Jennifer Hart; Douglas Hoffman; Wonhee Jang; Karen Karapetyan; Kenneth Katz; Chunlei Liu; Zenith Maddipatla; Adriana Malheiro; Kurt McDaniel; Michael Ovetsky; George Riley; George Zhou; J Bradley Holmes; Brandi L Kattman; Donna R Maglott
Journal:  Nucleic Acids Res       Date:  2018-01-04       Impact factor: 16.971

Review 8.  General guidelines for biomedical software development.

Authors:  Luis Bastiao Silva; Rafael C Jimenez; Niklas Blomberg; José Luis Oliveira
Journal:  F1000Res       Date:  2017-03-15

9.  Real-world integration of genomic data into the electronic health record: the PennChart Genomics Initiative.

Authors:  Kelsey S Lau-Min; Stephanie Byers Asher; Jessica Chen; Susan M Domchek; Michael Feldman; Steven Joffe; Jeffrey Landgraf; Virginia Speare; Lisa A Varughese; Sony Tuteja; Christine VanZandbergen; Marylyn D Ritchie; Katherine L Nathanson
Journal:  Genet Med       Date:  2020-12-10       Impact factor: 8.822

10.  Practical considerations in genomic decision support: The eMERGE experience.

Authors:  Timothy M Herr; Suzette J Bielinski; Erwin Bottinger; Ariel Brautbar; Murray Brilliant; Christopher G Chute; Beth L Cobb; Joshua C Denny; Hakon Hakonarson; Andrea L Hartzler; George Hripcsak; Joseph Kannry; Isaac S Kohane; Iftikhar J Kullo; Simon Lin; Shannon Manzi; Keith Marsolo; Casey Lynnette Overby; Jyotishman Pathak; Peggy Peissig; Jill Pulley; James Ralston; Luke Rasmussen; Dan M Roden; Gerard Tromp; Timothy Uphoff; Chunhua Weng; Wendy Wolf; Marc S Williams; Justin Starren
Journal:  J Pathol Inform       Date:  2015-09-28
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  1 in total

1.  A research agenda to support the development and implementation of genomics-based clinical informatics tools and resources.

Authors:  Ken Wiley; Laura Findley; Madison Goldrich; Tejinder K Rakhra-Burris; Ana Stevens; Pamela Williams; Carol J Bult; Rex Chisholm; Patricia Deverka; Geoffrey S Ginsburg; Eric D Green; Gail Jarvik; George A Mensah; Erin Ramos; Mary V Relling; Dan M Roden; Robb Rowley; Gil Alterovitz; Samuel Aronson; Lisa Bastarache; James J Cimino; Erin L Crowgey; Guilherme Del Fiol; Robert R Freimuth; Mark A Hoffman; Janina Jeff; Kevin Johnson; Kensaku Kawamoto; Subha Madhavan; Eneida A Mendonca; Lucila Ohno-Machado; Siddharth Pratap; Casey Overby Taylor; Marylyn D Ritchie; Nephi Walton; Chunhua Weng; Teresa Zayas-Cabán; Teri A Manolio; Marc S Williams
Journal:  J Am Med Inform Assoc       Date:  2022-07-12       Impact factor: 7.942

  1 in total

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