Literature DB >> 33978927

Endocannabinoid signaling pathways: beyond CB1R and CB2R.

Roger Gregory Biringer1.   

Abstract

The search for cannabinoid receptors other than CB1R and CB2R has been ongoing for over a decade. A number of orphan receptors have been proposed as potential cannabinoid receptors primarily based on phylogenic arguments and reactivity towards known endocannabinoids and phytocannabinoids. Seven putative cannabinoid receptors are described and discussed, and evidence for and against their inclusion in this category are presented.

Entities:  

Keywords:  2-Acyl glycerol; Anandamide; Cannabinoid; Endocannabinoid; Phytocannabinoid

Year:  2021        PMID： 33978927      PMCID： PMC8222499          DOI： 10.1007/s12079-021-00622-6

Source DB:  PubMed          Journal:  J Cell Commun Signal        ISSN： 1873-9601            Impact factor:   5.782


  144 in total

1.  Lysophosphatidic acid inhibits CD8 T cell activation and control of tumor progression.

Authors:  Shannon K Oda; Pamela Strauch; Yuko Fujiwara; Amin Al-Shami; Tamas Oravecz; Gabor Tigyi; Roberta Pelanda; Raul M Torres
Journal:  Cancer Immunol Res       Date:  2013-10       Impact factor: 11.151

2.  Developmental expression of GPR3 in rodent cerebellar granule neurons is associated with cell survival and protects neurons from various apoptotic stimuli.

Authors:  Shigeru Tanaka; Tatsuhiro Miyagi; Eisuke Dohi; Takahiro Seki; Izumi Hide; Yusuke Sotomaru; Yoshinaga Saeki; E Antonio Chiocca; Masayasu Matsumoto; Norio Sakai
Journal:  Neurobiol Dis       Date:  2014-04-24       Impact factor: 5.996

3.  Methods for the Development of In Silico GPCR Models.

Authors:  Paula Morales; Dow P Hurst; Patricia H Reggio
Journal:  Methods Enzymol       Date:  2017-07-14       Impact factor: 1.600

4.  Oxygenated metabolites of anandamide and 2-arachidonoylglycerol: conformational analysis and interaction with cannabinoid receptors, membrane transporter, and fatty acid amide hydrolase.

Authors:  Mario van der Stelt; J Albert van Kuik; Monica Bari; Guus van Zadelhoff; Bas R Leeflang; Gerrit A Veldink; Alessandro Finazzi-Agrò; Johannes F G Vliegenthart; Mauro Maccarrone
Journal:  J Med Chem       Date:  2002-08-15       Impact factor: 7.446

5.  Biased signaling of lipids and allosteric actions of synthetic molecules for GPR119.

Authors:  Helle A Hassing; Suzan Fares; Olav Larsen; Hamideh Pad; Maria Hauge; Robert M Jones; Thue W Schwartz; Harald S Hansen; Mette M Rosenkilde
Journal:  Biochem Pharmacol       Date:  2016-08-26       Impact factor: 5.858

6.  N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor.

Authors:  Douglas McHugh; Sherry S J Hu; Neta Rimmerman; Ana Juknat; Zvi Vogel; J Michael Walker; Heather B Bradshaw
Journal:  BMC Neurosci       Date:  2010-03-26       Impact factor: 3.288

7.  A role for beta-cell-expressed G protein-coupled receptor 119 in glycemic control by enhancing glucose-dependent insulin release.

Authors:  Zhi-Liang Chu; Robert M Jones; Hongmei He; Chris Carroll; Veronica Gutierrez; Annette Lucman; Molly Moloney; Hui Gao; Helen Mondala; Didier Bagnol; David Unett; Yin Liang; Keith Demarest; Graeme Semple; Dominic P Behan; James Leonard
Journal:  Endocrinology       Date:  2007-02-08       Impact factor: 4.736

8.  Cannabidiol, a novel inverse agonist for GPR12.

Authors:  Kevin J Brown; Alyssa S Laun; Zhao-Hui Song
Journal:  Biochem Biophys Res Commun       Date:  2017-09-06       Impact factor: 3.575

Review 9.  GPR3, GPR6, and GPR12 as novel molecular targets: their biological functions and interaction with cannabidiol.

Authors:  Alyssa S Laun; Sarah H Shrader; Kevin J Brown; Zhao-Hui Song
Journal:  Acta Pharmacol Sin       Date:  2018-06-25       Impact factor: 6.150

10.  Building a new conceptual framework for receptor heteromers.

Authors:  Sergi Ferré; Ruben Baler; Michel Bouvier; Marc G Caron; Lakshmi A Devi; Thierry Durroux; Kjell Fuxe; Susan R George; Jonathan A Javitch; Martin J Lohse; Ken Mackie; Graeme Milligan; Kevin D G Pfleger; Jean-Philippe Pin; Nora D Volkow; Maria Waldhoer; Amina S Woods; Rafael Franco
Journal:  Nat Chem Biol       Date:  2009-03       Impact factor: 15.040
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  5 in total

Review 1.  Medical Cannabis Activity Against Inflammation: Active Compounds and Modes of Action.

Authors:  Seegehalli M Anil; Hadar Peeri; Hinanit Koltai
Journal:  Front Pharmacol       Date:  2022-05-09       Impact factor: 5.988

Review 2.  Cannabis Biomolecule Effects on Cancer Cells and Cancer Stem Cells: Cytotoxic, Anti-Proliferative, and Anti-Migratory Activities.

Authors:  Hadar Peeri; Hinanit Koltai
Journal:  Biomolecules       Date:  2022-03-24

3.  Structure Prediction, Evaluation, and Validation of GPR18 Lipid Receptor Using Free Programs.

Authors:  Ilona Michalik; Kamil J Kuder; Katarzyna Kieć-Kononowicz; Jadwiga Handzlik
Journal:  Int J Mol Sci       Date:  2022-07-18       Impact factor: 6.208

Review 4.  Anti-Cancer Activity of Cannabis sativa Phytocannabinoids: Molecular Mechanisms and Potential in the Fight against Ovarian Cancer and Stem Cells.

Authors:  Hinanit Koltai; Nurit Shalev
Journal:  Cancers (Basel)       Date:  2022-09-01       Impact factor: 6.575

Review 5.  Cannabinoids in Chronic Pain: Therapeutic Potential Through Microglia Modulation.

Authors:  Nynke J van den Hoogen; Erika K Harding; Chloé E D Davidson; Tuan Trang
Journal:  Front Neural Circuits       Date:  2022-01-07       Impact factor: 3.492
  5 in total

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