Daryna Panicheva1, Pierre-Frédéric Villard2,3, Peter E Hammer4, Douglas Perrin5,4, Marie-Odile Berger6. 1. CNRS, Inria, LORIA, Université de Lorraine, Nancy, France. 2. CNRS, Inria, LORIA, Université de Lorraine, Nancy, France. pierrefrederic.villard@loria.fr. 3. Harvard School of Engineering and Applied Sciences, Cambridge, MA, USA. pierrefrederic.villard@loria.fr. 4. Harvard Medical School, Boston, MA, USA. 5. Harvard School of Engineering and Applied Sciences, Cambridge, MA, USA. 6. CNRS, Inria, LORIA, Université de Lorraine, Nancy, France. marie-odile.berger@inria.fr.
Abstract
PURPOSE: Mitral valve computational models are widely studied in the literature. They can be used for preoperative planning or anatomical understanding. Manual extraction of the valve geometry on medical images is tedious and requires special training, while automatic segmentation is still an open problem. METHODS: We propose here a fully automatic pipeline to extract the valve chordae architecture compatible with a computational model. First, an initial segmentation is obtained by sub-mesh topology analysis and RANSAC-like model-fitting procedure. Then, the chordal structure is optimized with respect to objective functions based on mechanical, anatomical, and image-based considerations. RESULTS: The approach has been validated on 5 micro-CT scans with a graph-based metric and has shown an [Formula: see text] accuracy rate. The method has also been tested within a structural simulation of the mitral valve closed state. CONCLUSION: Our results show that the chordae architecture resulting from our algorithm can give results similar to experienced users while providing an equivalent biomechanical simulation.
PURPOSE: Mitral valve computational models are widely studied in the literature. They can be used for preoperative planning or anatomical understanding. Manual extraction of the valve geometry on medical images is tedious and requires special training, while automatic segmentation is still an open problem. METHODS: We propose here a fully automatic pipeline to extract the valve chordae architecture compatible with a computational model. First, an initial segmentation is obtained by sub-mesh topology analysis and RANSAC-like model-fitting procedure. Then, the chordal structure is optimized with respect to objective functions based on mechanical, anatomical, and image-based considerations. RESULTS: The approach has been validated on 5 micro-CT scans with a graph-based metric and has shown an [Formula: see text] accuracy rate. The method has also been tested within a structural simulation of the mitral valve closed state. CONCLUSION: Our results show that the chordae architecture resulting from our algorithm can give results similar to experienced users while providing an equivalent biomechanical simulation.
Authors: Lukas Obermeier; Katharina Vellguth; Adriano Schlief; Lennart Tautz; Jan Bruening; Christoph Knosalla; Titus Kuehne; Natalia Solowjowa; Leonid Goubergrits Journal: Front Cardiovasc Med Date: 2022-03-22