| Literature DB >> 33978722 |
Elizabeth W Triche1, Xin Xin1,2, Sydnie Stackland1, Danielle Purvis1, Alexandra Harris1, Huihui Yu1,2, Jacqueline N Grady1, Shu-Xia Li1, Susannah M Bernheim1,3, Harlan M Krumholz1,2,4, James Poyer5, Karen Dorsey1,6.
Abstract
Importance: Present-on-admission (POA) indicators in administrative claims data allow researchers to distinguish between preexisting conditions and those acquired during a hospital stay. The impact of adding POA information to claims-based measures of hospital quality has not yet been investigated to better understand patient underlying risk factors in the International Statistical Classification of Diseases and Related Health Problems, Tenth Revision setting. Objective: To assess POA indicator use on Medicare claims and to assess the hospital- and patient-level outcomes associated with incorporating POA indicators in identifying risk factors for publicly reported outcome measures used by the Centers for Medicare & Medicaid Services (CMS). Design, Setting, and Participants: This comparative effectiveness study used national CMS claims data between July 1, 2015, and June 30, 2018. Six hospital quality measures assessing readmission and mortality outcomes were modified to include POA indicators in risk adjustment models. The models using POA were then compared with models using the existing complications-of-care algorithm to evaluate changes in risk model performance. Patient claims data were included for all Medicare fee-for-service and Veterans Administration beneficiaries aged 65 years or older with inpatient hospitalizations for acute myocardial infarction, heart failure, or pneumonia within the measurement period. Data were analyzed between September 2019 and March 2020. Main Outcomes and Measures: Changes in patient-level (C statistics) and hospital-level (quintile shifts in risk-standardized outcome rates) model performance after including POA indicators in risk adjustment.Entities:
Mesh:
Year: 2021 PMID: 33978722 PMCID: PMC8116982 DOI: 10.1001/jamanetworkopen.2021.8512
Source DB: PubMed Journal: JAMA Netw Open ISSN: 2574-3805
Cohort Description for Acute Myocardial Infarction, Heart Failure, and Pneumonia Mortality and Readmission Measures
| Characteristic | Admissions, No. (%) | |||||
|---|---|---|---|---|---|---|
| Mortality | Readmission | |||||
| Acute myocardial infarction (n = 491 366) | Heart failure (n = 1 055 330) | Pneumonia (n = 1 330 877) | Acute myocardial infarction (n = 502 198) | Heart failure (n = 1 252 347) | Pneumonia (n = 1 395 870) | |
| Hospitals, No. | 4304 | 4661 | 4723 | 4150 | 4665 | 4727 |
| With ≥25 claims | 2387 | 3690 | 4254 | 2197 | 3770 | 4254 |
| Male | 269 209 (54.8) | 506 550 (48.0) | 604 523 (45.4) | 276 668 (55.1) | 603 089 (48.2) | 677 158 (48.5) |
| Female | 222 157 (45.2) | 548 780 (52.0) | 726 354 (54.6) | 225 530 (44.9) | 649 258 (51.8) | 718 712 (51.5) |
| Age, mean (SD), y | 78.2(8.3) | 80.8 (8.5) | 80.5 (8.7) | 77.9 (8.3) | 80.6 (8.5) | 80.3 (8.7) |
Summary of Hospital-Level Present-on-Admission (POA) Indicator Use by Critical Access Hospital Status for AMI, HF, and PN Readmission and Mortality Measures, July 2015 to June 2018
| Measure cohort | POA indicator data available | Admissions, No. (%) | ||
|---|---|---|---|---|
| Non-CAH | CAH | All hospitals | ||
| AMI | Hospitals, No. | 3174 | 976 | 4150 |
| <20% missing | 3172 (99.9) | 798 (81.8) | 3970 (95.7) | |
| ≥20 to <80% missing | 2 (0.1) | 42 (4.3) | 44 (1.1) | |
| ≥80% missing | 0 | 136 (13.9) | 136 (3.3) | |
| HF | No. | 3327 | 1338 | 4665 |
| <20% missing | 3324 (99.9) | 1048 (78.3) | 4372 (93.7) | |
| ≥20 to <80% missing | 3 (0.1) | 116 (8.7) | 119 (2.6) | |
| ≥80% missing | 0 | 174 (13) | 174 (3.7) | |
| PN | No. | 3373 | 1354 | 4727 |
| <20% missing | 3369 (99.9) | 1064 (78.6) | 4433 (93.8) | |
| ≥20 to <80% missing | 4 (0.1) | 121 (8.9) | 125 (2.6) | |
| ≥80% missing | 0 | 169 (12.5) | 169 (3.6) | |
| AMI | No. | 3220 | 1084 | 4304 |
| <20% missing | 3217 (99.9) | 874 (80.6) | 4091 (95.1) | |
| ≥20 to <80% missing | 3 (0.1) | 61 (5.6) | 64 (1.5) | |
| ≥80% missing | 0 | 149 (13.7) | 149 (3.5) | |
| HF | No. | 3325 | 1336 | 4661 |
| <20% missing | 3324 (100) | 1047 (78.4) | 4371 (93.8) | |
| ≥20 to <80% missing | 1 (0) | 119 (8.9) | 120 (2.6) | |
| ≥80% missing | 0 | 170 (12.7) | 170 (3.6) | |
| PN | No. | 3370 | 1353 | 4723 |
| <20% missing | 3366 (99.9) | 1064 (78.6) | 4430 (93.8) | |
| ≥20 to <80% missing | 4 (0.1) | 117 (8.6) | 121 (2.6) | |
| ≥80% missing | 0 | 172 (12.7) | 172 (3.6) | |
Abbreviations: AMI, acute myocardial infarction; CAH, critical access hospital; HF, heart failure; POA, present on admission; PN, pneumonia.
Performance of Patient-Level AMI, HF, and PN Readmission and Mortality Measure Models Using Only the CoC Algorithm and Using POA Indicators
| Measure | Patients, No. | Current model using the CoC algorithm | Model with POA | ||
|---|---|---|---|---|---|
| Comorbidities per admission, mean (SD) | C statistic (95% CI) | Comorbidities per admission, mean (SD) | C statistic (95% CI) | ||
| AMI | 502 198 | 7.3 (4.01) | 0.658 (0.658-0.660) | 8.0 (3.9) | 0.662 (0.660-0.664) |
| HF | 1 252 347 | 11.4 (4.7) | 0.611 (0.610-0.612) | 12.2 (4.3) | 0.611 (0.609-0.612) |
| PN | 1 395 870 | 10.7 (5.4) | 0.637 (0.635-0.638) | 11.9 (5.0) | 0.638 (0.636-0.639) |
| AMI | 491 366 | 6.5 (3.2) | 0.728 (0.726-0.730) | 7.11 (3.2) | 0.774 (0.773-0.776) |
| HF | 1 055 330 | 7.9 (3.2) | 0.684 (0.683-0.686) | 8.4 (2.9) | 0.694 (0.692-0.695) |
| PN | 1 330 877 | 8.1 (4.2) | 0.720 (0.719-0.721) | 9.3 (4.0) | 0.743 (0.742-0.744) |
Abbreviations: AMI, acute myocardial infarction; CAHs, critical access hospitals; CoC, complications of care; HF, heart failure; PN, pneumonia; POA, present on admission.
All models also adjusted for age, sex, and history of coronary artery bypass grafting or percutaneous coronary intervention; however, these variables are not included in the average number of comorbidities included in the model. Patient-level models were calculated using logistic regression.
Using current Centers for Medicare & Medicaid Services (CMS) algorithm to distinguish POA conditions from CoC.
Using POA indicator as primary method of distinguishing conditions present on admission from complications of care; if POA indicators missing, current CMS algorithm was used.
Figure. Calibration Plots Comparing 6 Hospital Quality Measures Used by Centers for Medicare & Medicaid Services (CMS) With Models Including Present-on-Admission (POA) Indicators
AMI indicates acute myocardial infarction; HF, heart failure; PN, pneumonia.
Quintile Shifts in Risk-Standardized Outcome Rates With Addition of Present-on-Admission Indicators by CAH Status
| Measure | Total Non-CAHs, No. | Non-CAHs, No. (% of total non-CAHs) | Total CAHs, No. | CAHs, No. (% of total CAHs) | ||
|---|---|---|---|---|---|---|
| Shifting 1 quintile | Shifting 2 quintiles | Shifting 1 quintile | Shifting 2 quintiles | |||
| AMI | 2183 | 210 (9.6) | 0 | 14 | 4 (28.6) | 0 |
| HF | 3076 | 226 (7.3) | 0 | 694 | 52 (7.5) | 0 |
| PN | 3166 | 304 (9.6) | 0 | 1088 | 126 (11.6) | 0 |
| AMI | 2352 | 622 (26.4) | 13 (0.6) | 35 | 16 (45.8) | 3 (8.6) |
| HF | 3056 | 512 (16.8) | 0 | 634 | 100 (15.8) | 0 |
| PN | 3156 | 896 (28.4) | 24 (0.8) | 1089 | 294 (27.0) | 7 (0.6) |
Abbreviations: AMI, acute myocardial infarction; CAHs, critical access hospitals; HF, heart failure; PN, pneumonia.