Literature DB >> 33978331

Effect of age, gender, and time of day on pain-to-call times in patients with acute ST-segment elevation myocardial infarction: the CLOC’AGE study.

Frédéric Lapostolle1, Aurélie Loyeau2, Yasmine Beggaz3, Thévy Boche4, Virginie Pires5, Gaëlle Le Bail6, Lionel Lamhaut7, Benoît Simon8, François Dupas9, Alexandre Allonneau10, Jean-Michel Juliard11, Hakim Benamer12, Sarah Tepper3, Sophie Bataille13, Yves Lambert14.   

Abstract

BACKGROUND: The time lapse between onset of symptoms and a call to an emergency dispatch center (pain-to-call time) is a critical prognostic factor in patients with chest pain. It is therefore important to identify factors related to delays in calling for help.
OBJECTIVES: To analyze whether age, gender, or time of day influence the pain-to-call delay in patients with acute STsegment elevation myocardial infarction (STEMI).
MATERIAL AND METHODS: Data were extracted from a prospective registry of STEMI cases managed by 39 mobile intensive care ambulance teams before hospital arrival within 24 hours of onset in our region, the greater metropolitan area of Paris, France. We analyzed the relation between pain-to-call time and the following factors: age, gender, and the time of day when symptoms appeared. We also assessed the influence of pain-to-call time on the rate of prehospital decisions to implement reperfusion therapy.
RESULTS: A total of 24 662 consecutive patients were included; 19 291 (78%) were men and 4371 (22%) were women. The median age was 61 (interquartile range, 52-73) years (men, 59 [51-69] years; women, 73 [59-83] years; P .0001). The median pain-to-call time was 60 (24-164) minutes (men, 55 [23-150] minutes; women, 79 [31-220] minutes; P .0001). The delay varied by time of day from a median of 40 (17-101) minutes in men between 5 pm and 6 pm to 149 (43-377) minutes in women between 2 am and 3 am. The delay was longer in women regardless of time of day and increased significantly with age in both men and women (P .001). A longer pain-to-call time was significantly associated with a lower rate of implementation of myocardial reperfusion (P .001).
CONCLUSION: Pain-to-call delays were longer in women and older patients, especially at night. These age and gender differences identify groups that would benefit most from health education interventions.

Entities:  

Keywords:  Acute myocardial infarction.; Emergency health services; Infarto agudo de miocardio.; Pain-to-call time.; Sistema de Emergencias.; Tiempo de aviso a emergencias.

Mesh:

Year:  2021        PMID: 33978331

Source DB:  PubMed          Journal:  Emergencias        ISSN: 1137-6821            Impact factor:   3.881


  1 in total

1.  Interactions of ST-elevation myocardial infarction, age, and sex and the risk of major adverse cardiovascular events among Chinese adults: a secondary analysis of a single-centre prospective cohort.

Authors:  Cuiping Wang; Lin Zhou; Yi Liang; Peijing Liu; Wei Yuan
Journal:  BMJ Open       Date:  2022-07-12       Impact factor: 3.006

  1 in total

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