Literature DB >> 33975779

SchistoCyte Atlas: A Single-Cell Transcriptome Resource for Adult Schistosomes.

George R Wendt1, Michael L Reese2, James J Collins3.   

Abstract

Schistosomes cause untold disease and disability in the developing world. Here, we introduce SchistoCyte Atlas, a web-based platform for exploring gene expression at single-cell resolution in adult Schistosoma mansoni. Similar resources accessible to non-specialists across the globe will expedite our ability to understand the biology of these devastating parasites.
Copyright © 2021 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  RNAi screening; schistosome; single-cell RNAseq; web-based resource

Mesh：

Substances：

Year:  2021        PMID： 33975779      PMCID： PMC8721880          DOI： 10.1016/j.pt.2021.04.010

Source DB:  PubMed          Journal:  Trends Parasitol        ISSN： 1471-4922


  14 in total

1.  Quantification of clinical morbidity associated with schistosome infection in sub-Saharan Africa.

Authors:  Marieke J van der Werf; Sake J de Vlas; Simon Brooker; Caspar W N Looman; Nico J D Nagelkerke; J Dik F Habbema; Dirk Engels
Journal:  Acta Trop       Date:  2003-05       Impact factor: 3.112

2.  Large-scale RNAi screening uncovers therapeutic targets in the parasite Schistosoma mansoni.

Authors:  Jipeng Wang; Carlos Paz; Gilda Padalino; Avril Coghlan; Zhigang Lu; Irina Gradinaru; Julie N R Collins; Matthew Berriman; Karl F Hoffmann; James J Collins
Journal:  Science       Date:  2020-09-25       Impact factor: 47.728

3.  The global status of schistosomiasis and its control.

Authors:  L Chitsulo; D Engels; A Montresor; L Savioli
Journal:  Acta Trop       Date:  2000-10-23       Impact factor: 3.112

4.  Identification of new markers for the Schistosoma mansoni vitelline lineage.

Authors:  Jipeng Wang; James J Collins
Journal:  Int J Parasitol       Date:  2016-04-04       Impact factor: 3.981

5.  A gene expression atlas of adult Schistosoma mansoni and their gonads.

Authors:  Zhigang Lu; Florian Sessler; Nancy Holroyd; Steffen Hahnel; Thomas Quack; Matthew Berriman; Christoph G Grevelding
Journal:  Sci Data       Date:  2017-08-22       Impact factor: 6.444

Review 6.  Contributions of the Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) to Schistosomiasis Control and Elimination: Key Findings and Messages for Future Goals, Thresholds, and Operational Research.

Authors:  Daniel G Colley; Fiona M Fleming; Sultani H Matendechero; Stefanie Knopp; David Rollinson; Jürg Utzinger; Jennifer D Castleman; Nupur Kittur; Charles H King; Carl H Campbell; Fatma M Kabole; Safari Kinung'hi; Reda M R Ramzy; Sue Binder
Journal:  Am J Trop Med Hyg       Date:  2020-07       Impact factor: 2.345

7.  Stem cell heterogeneity drives the parasitic life cycle of Schistosoma mansoni.

Authors:  Jayhun Lee; Pengyang Li; Amir Saberi; Bo Wang; Huiying Yang; Chang Liu; Minglei Zhao; Phillip A Newmark
Journal:  Elife       Date:  2018-07-10       Impact factor: 8.140

8.  Single-cell analysis of Schistosoma mansoni identifies a conserved genetic program controlling germline stem cell fate.

Authors:  Dania Nanes Sarfati; Yuan Xue; Pengyang Li; Xi Yu; Alexander J Tarashansky; Stephen R Quake; Bo Wang
Journal:  Nat Commun       Date:  2021-01-20       Impact factor: 14.919

9.  A single-cell RNA-seq atlas of Schistosoma mansoni identifies a key regulator of blood feeding.

Authors:  George Wendt; Lu Zhao; Rui Chen; Chenxi Liu; Anthony J O'Donoghue; Conor R Caffrey; Michael L Reese; James J Collins
Journal:  Science       Date:  2020-09-25       Impact factor: 47.728

10.  Whole-organ isolation approach as a basis for tissue-specific analyses in Schistosoma mansoni.

Authors:  Steffen Hahnel; Zhigang Lu; R Alan Wilson; Christoph G Grevelding; Thomas Quack
Journal:  PLoS Negl Trop Dis       Date:  2013-07-25
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  5 in total

1.  Convergent evolution of a genotoxic stress response in a parasite-specific p53 homolog.

Authors:  George R Wendt; Divya A Shiroor; Carolyn E Adler; James J Collins
Journal:  Proc Natl Acad Sci U S A       Date:  2022-09-06       Impact factor: 12.779

Review 2.  Making sense of sensory behaviors in vector-borne helminths.

Authors:  Nicolas J Wheeler; Elissa A Hallem; Mostafa Zamanian
Journal:  Trends Parasitol       Date:  2022-08-02

3.  Schistosoma mansoni Fibroblast Growth Factor Receptor A Orchestrates Multiple Functions in Schistosome Biology and in the Host-Parasite Interplay.

Authors:  Xiaofeng Du; Donald P McManus; Conor E Fogarty; Malcolm K Jones; Hong You
Journal:  Front Immunol       Date:  2022-06-22       Impact factor: 8.786

4.  An atlas of the germ ball-cercaria-schistosomulum transition in Schistosoma mansoni, using confocal microscopy and in situ hybridisation.

Authors:  Sophie J Parker-Manuel; R Alan Wilson
Journal:  Curr Res Parasitol Vector Borne Dis       Date:  2022-04-12

5.  Schistosome Sulfotransferases: Mode of Action, Expression and Localization.

Authors:  Meghan A Guzman; Anastasia Rugel; Sevan N Alwan; Reid Tarpley; Alexander B Taylor; Frédéric D Chevalier; George R Wendt; James J Collins; Timothy J C Anderson; Stanton F McHardy; Philip T LoVerde
Journal:  Pharmaceutics       Date:  2022-07-06       Impact factor: 6.525
  5 in total

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