Literature DB >> 33972661

Novel AI driven approach to classify infant motor functions.

Simon Reich1, Dajie Zhang1,2,3, Tomas Kulvicius1,4, Sven Bölte5, Karin Nielsen-Saines6, Florian B Pokorny2,7, Robert Peharz8, Luise Poustka1,3, Florentin Wörgötter3,4, Christa Einspieler2, Peter B Marschik9,10,11,12.   

Abstract

The past decade has evinced a boom of computer-based approaches to aid movement assessment in early infancy. Increasing interests have been dedicated to develop AI driven approaches to complement the classic Prechtl general movements assessment (GMA). This study proposes a novel machine learning algorithm to detect an age-specific movement pattern, the fidgety movements (FMs), in a prospectively collected sample of typically developing infants. Participants were recorded using a passive, single camera RGB video stream. The dataset of 2800 five-second snippets was annotated by two well-trained and experienced GMA assessors, with excellent inter- and intra-rater reliabilities. Using OpenPose, the infant full pose was recovered from the video stream in the form of a 25-points skeleton. This skeleton was used as input vector for a shallow multilayer neural network (SMNN). An ablation study was performed to justify the network's architecture and hyperparameters. We show for the first time that the SMNN is sufficient to discriminate fidgety from non-fidgety movements in a sample of age-specific typical movements with a classification accuracy of 88%. The computer-based solutions will complement original GMA to consistently perform accurate and efficient screening and diagnosis that may become universally accessible in daily clinical practice in the future.

Entities:  

Year:  2021        PMID: 33972661     DOI: 10.1038/s41598-021-89347-5

Source DB:  PubMed          Journal:  Sci Rep        ISSN: 2045-2322            Impact factor:   4.379


  20 in total

Review 1.  General movement assessment as a method of developmental neurology: new paradigms and their consequences. The 1999 Ronnie MacKeith lecture.

Authors:  H F Prechtl
Journal:  Dev Med Child Neurol       Date:  2001-12       Impact factor: 5.449

2.  En route to disentangle the impact and neurobiological substrates of early vocalizations: learning from Rett syndrome.

Authors:  Peter B Marschik; Walter E Kaufmann; Sven Bölte; Jeff Sigafoos; Christa Einspieler
Journal:  Behav Brain Sci       Date:  2014-12       Impact factor: 12.579

3.  Quantitative score for the evaluation of kinematic recordings in neuropediatric diagnostics. Detection of complex patterns in spontaneous limb movements.

Authors:  D Karch; K Wochner; K Kim; H Philippi; M Hadders-Algra; J Pietz; H Dickhaus
Journal:  Methods Inf Med       Date:  2010-06-07       Impact factor: 2.176

4.  An early marker for neurological deficits after perinatal brain lesions.

Authors:  H F Prechtl; C Einspieler; G Cioni; A F Bos; F Ferrari; D Sontheimer
Journal:  Lancet       Date:  1997-05-10       Impact factor: 79.321

Review 5.  Predictive validity of spontaneous early infant movement for later cerebral palsy: a systematic review.

Authors:  Amanda K L Kwong; Tara L Fitzgerald; Lex W Doyle; Jeanie L Y Cheong; Alicia J Spittle
Journal:  Dev Med Child Neurol       Date:  2018-02-22       Impact factor: 5.449

6.  Quantification of the segmental kinematics of spontaneous infant movements.

Authors:  Dominik Karch; Keun-Sun Kim; Katarzyna Wochner; Joachim Pietz; Hartmut Dickhaus; Heike Philippi
Journal:  J Biomech       Date:  2008-08-15       Impact factor: 2.712

Review 7.  A systematic review of tests to predict cerebral palsy in young children.

Authors:  Margot Bosanquet; Lisa Copeland; Robert Ware; Roslyn Boyd
Journal:  Dev Med Child Neurol       Date:  2013-05       Impact factor: 5.449

8.  The motor repertoire in 3- to 5-month old infants with Down syndrome.

Authors:  Dafne Herrero; Christa Einspieler; Carolina Y Panvequio Aizawa; Akmer Mutlu; Hong Yang; Alice Nogolová; Jasmin Pansy; Karin Nielsen-Saines; Peter B Marschik
Journal:  Res Dev Disabil       Date:  2017-06-03

9.  Cerebral Palsy: Early Markers of Clinical Phenotype and Functional Outcome.

Authors:  Christa Einspieler; Arend F Bos; Magdalena Krieber-Tomantschger; Elsa Alvarado; Vanessa M Barbosa; Natascia Bertoncelli; Marlette Burger; Olena Chorna; Sabrina Del Secco; Raye-Ann DeRegnier; Britta Hüning; Jooyeon Ko; Laura Lucaccioni; Tomoki Maeda; Viviana Marchi; Erika Martín; Catherine Morgan; Akmer Mutlu; Alice Nogolová; Jasmin Pansy; Colleen Peyton; Florian B Pokorny; Lucia R Prinsloo; Eileen Ricci; Lokesh Saini; Anna Scheuchenegger; Cinthia R D Silva; Marina Soloveichick; Alicia J Spittle; Moreno Toldo; Fabiana Utsch; Jeanetta van Zyl; Carlos Viñals; Jun Wang; Hong Yang; Bilge N Yardımcı-Lokmanoğlu; Giovanni Cioni; Fabrizio Ferrari; Andrea Guzzetta; Peter B Marschik
Journal:  J Clin Med       Date:  2019-10-04       Impact factor: 4.241

Review 10.  The General Movement Assessment Helps Us to Identify Preterm Infants at Risk for Cognitive Dysfunction.

Authors:  Christa Einspieler; Arend F Bos; Melissa E Libertus; Peter B Marschik
Journal:  Front Psychol       Date:  2016-03-22
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  5 in total

1.  A semi-automatic toolbox for markerless effective semantic feature extraction.

Authors:  Vito Paolo Pastore; Matteo Moro; Francesca Odone
Journal:  Sci Rep       Date:  2022-07-13       Impact factor: 4.996

2.  Development and Validation of a Deep Learning Method to Predict Cerebral Palsy From Spontaneous Movements in Infants at High Risk.

Authors:  Daniel Groos; Lars Adde; Sindre Aubert; Lynn Boswell; Raye-Ann de Regnier; Toril Fjørtoft; Deborah Gaebler-Spira; Andreas Haukeland; Marianne Loennecken; Michael Msall; Unn Inger Möinichen; Aurelie Pascal; Colleen Peyton; Heri Ramampiaro; Michael D Schreiber; Inger Elisabeth Silberg; Nils Thomas Songstad; Niranjan Thomas; Christine Van den Broeck; Gunn Kristin Øberg; Espen A F Ihlen; Ragnhild Støen
Journal:  JAMA Netw Open       Date:  2022-07-01

3.  Healthcare applications of single camera markerless motion capture: a scoping review.

Authors:  Bradley Scott; Martin Seyres; Fraser Philp; Edward K Chadwick; Dimitra Blana
Journal:  PeerJ       Date:  2022-05-26       Impact factor: 3.061

Review 4.  Video-Based Automatic Baby Motion Analysis for Early Neurological Disorder Diagnosis: State of the Art and Future Directions.

Authors:  Marco Leo; Giuseppe Massimo Bernava; Pierluigi Carcagnì; Cosimo Distante
Journal:  Sensors (Basel)       Date:  2022-01-24       Impact factor: 3.576

5.  Deep learning-based quantitative analyses of spontaneous movements and their association with early neurological development in preterm infants.

Authors:  Hyun Iee Shin; Hyung-Ik Shin; Moon Suk Bang; Don-Kyu Kim; Seung Han Shin; Ee-Kyung Kim; Yoo-Jin Kim; Eun Sun Lee; Seul Gi Park; Hye Min Ji; Woo Hyung Lee
Journal:  Sci Rep       Date:  2022-02-24       Impact factor: 4.379

  5 in total

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